ID A8MXL7_HUMAN Unreviewed; 545 AA. AC A8MXL7; DT 04-DEC-2007, integrated into UniProtKB/TrEMBL. DT 04-DEC-2007, sequence version 1. DT 09-FEB-2010, entry version 21. DE SubName: Full=cDNA FLJ37274 fis, clone BRAMY2012162, highly similar to Kinesin light chain 2; DE SubName: Full=Putative uncharacterized protein KLC2; GN Name=KLC2; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP IDENTIFICATION. RG Ensembl; RL Submitted (OCT-2009) to UniProtKB. RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=16554811; DOI=10.1038/nature04632; RA Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., RA Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., RA Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., RA FitzGerald M.G., Jaffe D.B., LaButti K., Nicol R., Park H.-S., RA Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., RA Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., RA Sakaki Y.; RT "Human chromosome 11 DNA sequence and analysis including novel gene RT identification."; RL Nature 440:497-500(2006). RN [3] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Amygdala; RX PubMed=14702039; DOI=10.1038/ng1285; RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.; RT "Complete sequencing and characterization of 21,243 full-length human RT cDNAs."; RL Nat. Genet. 36:40-45(2004). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AP000759; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AP001107; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AK094593; BAG52895.1; -; mRNA. DR IPI; IPI00793613; -. DR RefSeq; NP_001128246.1; -. DR UniGene; Hs.280792; -. DR SMR; A8MXL7; 140-402. DR STRING; A8MXL7; -. DR PRIDE; A8MXL7; -. DR Ensembl; ENST00000394066; ENSP00000377630; ENSG00000174996; Homo sapiens. DR Ensembl; ENST00000421552; ENSP00000408484; ENSG00000174996; Homo sapiens. DR Ensembl; ENST00000452607; ENSP00000389171; ENSG00000174996; Homo sapiens. DR GeneID; 64837; -. DR KEGG; hsa:64837; -. DR UCSC; uc001ohd.1; human. DR CTD; 64837; -. DR HGNC; HGNC:20716; KLC2. DR Bgee; A8MXL7; -. DR GO; GO:0005871; C:kinesin complex; IEA:InterPro. DR GO; GO:0005488; F:binding; IEA:InterPro. DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro. DR InterPro; IPR002151; Kinesin_light. DR InterPro; IPR015792; Kinesin_light_repeat. DR InterPro; IPR015390; Rabaptin_Rab5-bd. DR InterPro; IPR013026; TPR-contain. DR InterPro; IPR011990; TPR-like_helical. DR InterPro; IPR019734; TPR_repeat. DR Gene3D; G3DSA:1.25.40.10; TPR-like_helical; 1. DR Pfam; PF09311; Rab5-bind; 1. DR PRINTS; PR00381; KINESINLIGHT. DR SMART; SM00028; TPR; 4. DR PROSITE; PS01160; KINESIN_LIGHT; 2. DR PROSITE; PS50005; TPR; 5. DR PROSITE; PS50293; TPR_REGION; 1. PE 2: Evidence at transcript level; KW Repeat; TPR repeat. SQ SEQUENCE 545 AA; 60047 MW; B30B27FA163B5D47 CRC64; MAMMVFPREE KLSQDEIVLG TKAVIQGLET LRGEHRALLA PLVAPEAGEA EPGSQERCIL LRRSLEAIEL GLGEAQEEKG DVPKDTLDDL FPNEDEQSPA PSPGGGDVSG QHGGYEIPAR LRTLHNLVIQ YASQGRYEVA VPLCKQALED LEKTSGHDHP DVATMLNILA LVYRDQNKYK EAAHLLNDAL AIREKTLGKD HPAVAATLNN LAVLYGKRGK YKEAEPLCKR ALEIREKVLG KFHPDVAKQL SNLALLCQNQ GKAEEVEYYY RRALEIYATR LGPDDPNVAK TKNNLASCYL KQGKYQDAET LYKEILTRAH EKEFGSVNGD NKPIWMHAEE REESKDKRRD SAPYGEYGSW YKACKVDSPT VNTTLRSLGA LYRRQGKLEA AHTLEDCASR NRKQGLDPAS QTKVVELLKD GSGRRGDRRS SRDMAGGAGP RSESDLEDVG PTAEWNGDGS GSLRRSGSFG KLRDALRRSS EMLVKKLQGG TPQEPPNPRM KRASSLNFLN KSVEEPTQPG GTGLSDSRTL SSSSMDLSRR SSLVG //