ID A8K2W4_HUMAN Unreviewed; 592 AA. AC A8K2W4; DT 04-DEC-2007, integrated into UniProtKB/TrEMBL. DT 04-DEC-2007, sequence version 1. DT 03-JUL-2019, entry version 66. DE SubName: Full=cDNA FLJ76247, highly similar to Homo sapiens BRCA1 associated protein (BRAP), mRNA {ECO:0000313|EMBL:BAF83068.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:BAF83068.1}; RN [1] {ECO:0000313|EMBL:BAF83068.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Tongue {ECO:0000313|EMBL:BAF83068.1}; RA Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., RA Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., RA Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., RA Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.; RT "NEDO human cDNA sequencing project."; RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK290379; BAF83068.1; -; mRNA. DR PeptideAtlas; A8K2W4; -. DR PRIDE; A8K2W4; -. DR eggNOG; KOG0804; Eukaryota. DR eggNOG; ENOG410XSS2; LUCA. DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR CDD; cd12718; RRM_BRAP2; 1. DR Gene3D; 3.30.40.10; -; 2. DR InterPro; IPR011422; BRAP2. DR InterPro; IPR034932; BRAP2_RRM. DR InterPro; IPR035979; RBD_domain_sf. DR InterPro; IPR001841; Znf_RING. DR InterPro; IPR013083; Znf_RING/FYVE/PHD. DR InterPro; IPR001607; Znf_UBP. DR Pfam; PF07576; BRAP2; 1. DR Pfam; PF13639; zf-RING_2; 1. DR Pfam; PF02148; zf-UBP; 1. DR SMART; SM00184; RING; 1. DR SMART; SM00290; ZnF_UBP; 1. DR SUPFAM; SSF54928; SSF54928; 1. DR PROSITE; PS50089; ZF_RING_2; 1. DR PROSITE; PS50271; ZF_UBP; 1. PE 2: Evidence at transcript level; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175}; KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175}; KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}. FT DOMAIN 264 304 RING-type. {ECO:0000259|PROSITE:PS50089}. FT DOMAIN 315 376 UBP-type. {ECO:0000259|PROSITE:PS50271}. FT ZN_FING 315 376 UBP-type. {ECO:0000256|PROSITE-ProRule: FT PRU00502}. FT REGION 78 124 Disordered. {ECO:0000256|MobiDB-lite: FT A8K2W4}. FT REGION 565 592 Disordered. {ECO:0000256|MobiDB-lite: FT A8K2W4}. FT COILED 438 507 {ECO:0000256|SAM:Coils}. FT COMPBIAS 82 111 Polyampholyte. {ECO:0000256|MobiDB-lite: FT A8K2W4}. SQ SEQUENCE 592 AA; 67298 MW; 28AC1B5E1ED49500 CRC64; MSVSLVVIRL ELAEHSPVPA GFGFSAAAGE MSDEEIKKTT LASAVACLEG KSPGEKVAII HQHLGRREMT DVIIETMKSN PDELKTTVEE RKSSEASPTA QRSKDHSKEC INAAPDSPSK QLPDQISFFS GNPSVEIVHG IMHLYKTNKM TSLKEDVRRS AMLCILTVPA AMTSHDLMKF VAPFNEVIEQ MKIIRDSTPN QYMVLIKFRA QADADSFYMT CNGRQFNSIE DDVCQLVYVE RAEVLKSEDG ASLPVMDLTE LPKCTVCLER MDESVNGILT TLCNHSFHSQ CLQRWDDTTC PVCRYCQTPE PVEENKCFEC GVQENLRICL ICGHIGCGRY VSRHAYKHFE ETQHTYAMQL TNHRVWDYAG DNYVHRLVAS KTDGKIVQYE CEGDTCQEEK IDALQLEYSY LLTSQLESQR IYWEHKIVRI EKDTAEEINN MKTKFKETIE KCDNLEHKLN DLLKEKQSVE RKCTQLNTKV AKLTNELKEE QEMNKCLRAN QVLLQNKLKE EERVLKETCD QKDLQITEIQ EQLRDVMFYL ETQQKINHLP AETRQEIQEG QINIAMASAS SPASSGGSGK LPSRKGRSKR GK //