ID   A8HR89_PODAS            Unreviewed;       926 AA.
AC   A8HR89;
DT   04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT   04-DEC-2007, sequence version 1.
DT   13-SEP-2023, entry version 83.
DE   SubName: Full=Heat shock protein HSP104 {ECO:0000313|EMBL:ABV71346.1};
OS   Podospora anserina (Pleurage anserina).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Podosporaceae; Podospora.
OX   NCBI_TaxID=2587412 {ECO:0000313|EMBL:ABV71346.1};
RN   [1] {ECO:0000313|EMBL:ABV71346.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=17881723; DOI=10.1091/mbc.E07-07-0657;
RA   Malato L., Dos Reis S., Benkemoun L., Sabate R., Saupe S.J.;
RT   "Role of Hsp104 in the propagation and inheritance of the [Het-s] prion.";
RL   Mol. Biol. Cell 18:4803-4812(2007).
CC   -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC       {ECO:0000256|RuleBase:RU004432}.
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DR   EMBL; EU128751; ABV71346.1; -; Genomic_DNA.
DR   AlphaFoldDB; A8HR89; -.
DR   VEuPathDB; FungiDB:PODANS_7_8800; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   CDD; cd00009; AAA; 1.
DR   CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR019489; Clp_ATPase_C.
DR   InterPro; IPR036628; Clp_N_dom_sf.
DR   InterPro; IPR004176; Clp_R_dom.
DR   InterPro; IPR001270; ClpA/B.
DR   InterPro; IPR018368; ClpA/B_CS1.
DR   InterPro; IPR028299; ClpA/B_CS2.
DR   InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR   PANTHER; PTHR11638:SF18; HEAT SHOCK PROTEIN 104; 1.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF07724; AAA_2; 1.
DR   Pfam; PF17871; AAA_lid_9; 1.
DR   Pfam; PF02861; Clp_N; 1.
DR   Pfam; PF10431; ClpB_D2-small; 1.
DR   PRINTS; PR00300; CLPPROTEASEA.
DR   SMART; SM00382; AAA; 2.
DR   SMART; SM01086; ClpB_D2-small; 1.
DR   SUPFAM; SSF81923; Double Clp-N motif; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51903; CLP_R; 1.
DR   PROSITE; PS00870; CLPAB_1; 1.
DR   PROSITE; PS00871; CLPAB_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW   Chaperone {ECO:0000256|RuleBase:RU004432};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU004432};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW   ProRule:PRU01251}; Stress response {ECO:0000313|EMBL:ABV71346.1}.
FT   DOMAIN          1..162
FT                   /note="Clp R"
FT                   /evidence="ECO:0000259|PROSITE:PS51903"
FT   COILED          431..545
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   926 AA;  103091 MW;  51B0E078F20B9785 CRC64;
     MNSKMEFTDR AKKALEDAMA LAEQYAHSQL LPVHLAVALL DPLPDQSKDL QNAPPGTTQT
     LLRQVVERAH GDPQLFDRAL KKMLVRLPSQ DPPPESVSMA PSFNNVLRKA MELQKVQKDT
     YIAVDHLIQA LSEDVSIQGA LKEANIPKPK LVQEAVQQIR GTKRVDSRNA DTEQENENLA
     KFTIDMTAMA REGKIDPVIG REEEIRRVVR ILSRRTKNNP VLIGEPGVGK TTVVEGLAQR
     IVNNDVPDNL AACKLLSLDV GALVAGSKYR GEFEERMKGV LKEIQESKEM IVLFVDEIHL
     LMGAGSSGEG GMDAANLLKP MLARGQLHCI GATTLAEYRK YIEKDAAFER RFQQVLVKEP
     TIPETISILR GLKEKYEVHH GVNIADAAIV ASANLAARYL TSRRLPDSAV DLIDEAAAAV
     RVARESQPEI IDSLERRLRQ LKIEIHALSR EKDEASKTRL AQARQDAENV EEELRPLREK
     YERERQRGKD IQEAKLKLEA LRVKAEDASR VGDHSRAADL QYYAIPEQEA VIRRLEKEKA
     AADAALNANG GDSGGSMITD VVGPDQINEI VARWTGIPVT RLKTTEREKL LHMEKALGKI
     VVGQKEAVQS VSNAIRLQRS GLANPNQPPS FLFCGPSGTG KTLLTKALAE FLFDDPKSMI
     RFDMSEYQER HSLSRMIGAP PGYVGHDSGG QLTEALRRKP FSILLFDEVE KAAKEVLTVL
     LQLMDDGRIT DGQGRVVDAK NCIVVMTSNL GAEYLARPNG KDGKIDPTTR ELVMNALRNY
     FLPEFLNRIN SIVIFNRLTR KEIRRIVDLR ISEIQKRLSD NDRNVIIKVS EAAKDKLGAQ
     GYSPAYGARP LQRLLEKEVL NRMAILILRG SIRDGEVARV DLVDNKVTVL PNHQESEASD
     EEMMIDSDDA LDEIAPDSMD EDLYND
//