ID A8BFP4_GIAIC Unreviewed; 114 AA. AC A8BFP4; DT 13-NOV-2007, integrated into UniProtKB/TrEMBL. DT 13-NOV-2007, sequence version 1. DT 26-FEB-2020, entry version 56. DE SubName: Full=Macrophage migration inhibitory factor {ECO:0000313|EMBL:EDO79637.1}; GN ORFNames=GL50803_12091 {ECO:0000313|EMBL:EDO79637.1}; OS Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia). OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia. OX NCBI_TaxID=184922 {ECO:0000313|EMBL:EDO79637.1, ECO:0000313|Proteomes:UP000001548}; RN [1] {ECO:0000313|EMBL:EDO79637.1, ECO:0000313|Proteomes:UP000001548} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 50803 / WB clone C6 {ECO:0000313|Proteomes:UP000001548}; RX PubMed=17901334; DOI=10.1126/science.1143837; RA Morrison H.G., McArthur A.G., Gillin F.D., Aley S.B., Adam R.D., RA Olsen G.J., Best A.A., Cande W.Z., Chen F., Cipriano M.J., Davids B.J., RA Dawson S.C., Elmendorf H.G., Hehl A.B., Holder M.E., Huse S.M., Kim U.U., RA Lasek-Nesselquist E., Manning G., Nigam A., Nixon J.E., Palm D., RA Passamaneck N.E., Prabhu A., Reich C.I., Reiner D.S., Samuelson J., RA Svard S.G., Sogin M.L.; RT "Genomic minimalism in the early diverging intestinal parasite Giardia RT lamblia."; RL Science 317:1921-1926(2007). RN [2] {ECO:0000213|PDB:3T5S} RP X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS). RX PubMed=23709284; DOI=10.1007/s10969-013-9155-9; RA Buchko G.W., Abendroth J., Robinson H., Zhang Y., Hewitt S.N., RA Edwards T.E., Van Voorhis W.C., Myler P.J.; RT "Crystal structure of a macrophage migration inhibitory factor from Giardia RT lamblia."; RL J. Struct. Funct. Genomics 14:47-57(2013). CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:EDO79637.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AACB02000015; EDO79637.1; -; Genomic_DNA. DR RefSeq; XP_001707311.1; XM_001707259.1. DR PDB; 3T5S; X-ray; 2.30 A; A=1-114. DR PDBsum; 3T5S; -. DR SMR; A8BFP4; -. DR EnsemblProtists; EDO79637; EDO79637; GL50803_12091. DR GeneID; 5700210; -. DR KEGG; gla:GL50803_12091; -. DR EuPathDB; GiardiaDB:GL50803_12091; -. DR eggNOG; KOG1759; Eukaryota. DR eggNOG; ENOG41122MF; LUCA. DR HOGENOM; CLU_129906_4_1_1; -. DR InParanoid; A8BFP4; -. DR OMA; MPLIKVQ; -. DR OrthoDB; 1451925at2759; -. DR Proteomes; UP000001548; Unassembled WGS sequence. DR Gene3D; 3.30.429.10; -; 1. DR InterPro; IPR001398; Macrophage_inhib_fac. DR InterPro; IPR014347; Tautomerase/MIF_sf. DR PANTHER; PTHR11954; PTHR11954; 1. DR Pfam; PF01187; MIF; 1. DR SUPFAM; SSF55331; SSF55331; 1. PE 1: Evidence at protein level; KW 3D-structure {ECO:0000213|PDB:3T5S}; KW Reference proteome {ECO:0000313|Proteomes:UP000001548}. SQ SEQUENCE 114 AA; 12368 MW; C7BDC762C6B2E3FA CRC64; MPCAIVTTNA DFTKDQADAF CLDMGQVLAK ETGKPVSYCM AGVRKADMSF GTSTDLCCFV DFYCIGVISQ AKNPSISAAI TGCLTQHFKV KPERVYISFN EAKGHNWGFN GSTF //