ID A7XYN8_CHLTH Unreviewed; 185 AA. AC A7XYN8; DT 23-OCT-2007, integrated into UniProtKB/TrEMBL. DT 23-OCT-2007, sequence version 1. DT 16-OCT-2013, entry version 35. DE SubName: Full=MurA; DE Flags: Fragment; GN Name=murA; ORFNames=CT455; OS Chlamydia trachomatis. OC Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae; OC Chlamydia/Chlamydophila group; Chlamydia. OX NCBI_TaxID=813; RN [1] RP NUCLEOTIDE SEQUENCE. RA DeMars R.I., Weinfurter J.T.; RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE. RX PubMed=18083799; DOI=10.1128/JB.01592-07; RA DeMars R., Weinfurter J.; RT "Interstrain gene transfer in Chlamydia trachomatis in vitro: RT mechanism and significance."; RL J. Bacteriol. 190:1605-1614(2008). CC -!- FUNCTION: Cell wall formation. Adds enolpyruvyl to UDP-N- CC acetylglucosamine (By similarity). CC -!- CATALYTIC ACTIVITY: Phosphoenolpyruvate + UDP-N-acetyl-alpha-D- CC glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha- CC D-glucosamine. CC -!- PATHWAY: Cell wall biogenesis; peptidoglycan biosynthesis. CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EU105039; ABV03243.1; -; Genomic_DNA. DR ProteinModelPortal; A7XYN8; -. DR UniPathway; UPA00219; -. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0008760; F:UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity; IEA:InterPro. DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW. DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW. DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-UniPathway. DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW. DR GO; GO:0019277; P:UDP-N-acetylgalactosamine biosynthetic process; IEA:InterPro. DR Gene3D; 3.65.10.10; -; 2. DR InterPro; IPR001986; Enolpyruvate_Tfrase_dom. DR InterPro; IPR013792; RNA3'P_cycl/enolpyr_Trfase_a/b. DR InterPro; IPR005750; UDP_GlcNAc_COvinyl_MurA. DR PANTHER; PTHR21090:SF4; PTHR21090:SF4; 1. DR Pfam; PF00275; EPSP_synthase; 1. DR SUPFAM; SSF55205; SSF55205; 1. PE 3: Inferred from homology; KW Cell cycle; Cell division; Cell shape; KW Cell wall biogenesis/degradation; Cytoplasm; Peptidoglycan synthesis; KW Transferase. FT NON_TER 1 1 FT NON_TER 185 185 SQ SEQUENCE 185 AA; 20167 MW; E36F3E3724E62BDB CRC64; KKLGAEIVIS DEGYWASAPN GLVGAHITLP YPSVGATENL ILASVGAQGR TIIKNAALEV EIIDLIVFLQ KAGVEITTDN DKTIEIFGCQ DFYSVEHFII PDKIEAASFG MAAVVSQGRI FVEQARHEHM IPFLKVLRSI GGGFSVHENG IEFFYDKPLK GGVLLETDVH PGFITDWQQP FAVLL //