ID A6VYL7_9GAMM Unreviewed; 310 AA. AC A6VYL7; DT 21-AUG-2007, integrated into UniProtKB/TrEMBL. DT 21-AUG-2007, sequence version 1. DT 23-OCT-2007, entry version 3. DE tRNA delta(2)-isopentenylpyrophosphate transferase (EC 2.5.1.8). GN ORFNames=Mmwyl1_2633; OS Marinomonas sp. MWYL1. OC Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales; OC Marinomonas. OX NCBI_TaxID=400668; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=MWYL1; RG US DOE Joint Genome Institute; RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., RA Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., RA Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., RA Kyrpides N., Kim E., Johnston A.W.B., Todd J.D., Rogers R., Wexler M., RA Bond P.L., Li Y., Richardson P.; RT "Complete sequence of Marinomonas sp. MWYL1."; RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Catalyzes the first step in the biosynthesis of 2- CC methylthio-N6-(delta(2)-isopentenyl)-adenosine (MS[2]I[6]A) CC adjacent to the anticodon of several tRNA species (By similarity). CC -!- CATALYTIC ACTIVITY: Isopentenyl diphosphate + tRNA = diphosphate + CC tRNA containing 6-isopentenyladenosine. CC -!- SIMILARITY: Belongs to the IPP transferase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000749; ABR71546.1; -; Genomic_DNA. DR RefSeq; YP_001341481.1; -. DR GeneID; 5365666; -. DR InterPro; IPR002627; IPPT. DR InterPro; IPR011593; IPPtrans_like. DR PANTHER; PTHR11088; IPPT; 1. DR Pfam; PF01715; IPPT; 1. DR ProDom; PD004674; IPPT; 1. DR ProDom; PD005388; IPPtrans_like; 1. DR TIGRFAMs; TIGR00174; miaA; 1. PE 3: Inferred from homology; KW ATP-binding; Nucleotide-binding; Nucleotidyltransferase; Transferase; KW tRNA processing. SQ SEQUENCE 310 AA; 35239 MW; 013911EA1DEDA547 CRC64; MTKPYVVCLM GPTASGKTGL AVELAEHHNF EIISVDSALV YKGMDIGTAK PSAELLARAP HRLIDIIDPL EFYSAADFVL DAVEQSQEIL AKGKTPLLVG GTMMYFNALQ KGLAEMPQAD AELRVIIEAE AAEKGWAALH EELQRFDPEA ASRIHPNDPQ RLQRAIEVYR LTGKTMTHFW RQQEAVSLPF EMINMAVMPK ERSVLHERIE QRFYDMMDQG FLAEVEGFYR RGDLTIDMPS MRCVGYRQLW QYLDGVDLLE DAIFKGVVAS RQLAKRQLTW LRGWEDLMIF DSLSKDLVPE ALNYIESRII //