ID A6TGP0_KLEPN Unreviewed; 1353 AA. AC A6TGP0; DT 21-AUG-2007, integrated into UniProtKB/TrEMBL. DT 21-AUG-2007, sequence version 1. DT 02-OCT-2007, entry version 2. DE DNA-directed RNA polymerase (EC 2.7.7.6). GN Name=rpoB; ORFNames=KPN_04365; OS Klebsiella pneumoniae subsp. pneumoniae MGH 78578. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Klebsiella. OX NCBI_TaxID=272620; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=ATCC 700721; RG The Klebsiella pneumonia Genome Sequencing Project; RA McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P., RA Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.; RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription CC of DNA into RNA using the four ribonucleoside triphosphates as CC substrates (By similarity). CC -!- CATALYTIC ACTIVITY: Nucleoside triphosphate + RNA(n) = diphosphate CC + RNA(n+1). CC -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 CC beta' and 1 omega subunit. When a sigma factor is associated with CC the core the holoenzyme is formed, which can initiate CC transcription (By similarity). CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000647; ABR79724.1; -; Genomic_DNA. DR RefSeq; YP_001337991.1; -. DR GeneID; 5342619; -. PE 3: Inferred from homology; KW DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription; KW Transferase. SQ SEQUENCE 1353 AA; 151770 MW; D3EBC723774C2A2F CRC64; MGRLVSELRN PMVYSYTEKK RIRKDFGKRP QVLDVPYLLS IQLDSFQKFI EQDPEGQYGL EAAFRSVFPI QSYSGNSELQ YVSYRLGEPV FDVKECQIRG VTYSAPLRVK LRLVIYEREA PEGTVKDIKE QEVYMGEIPL MTDNGTFVIN GTERVIVSQL HRSPGVFFDS DKGKTHSSGK VLYNARIIPY RGSWLDFEFD PKDNLFVRID RRRKLPATII LRALNYTTEQ ILDLFFEKVV FEIRDNKLQM ELIPERLRGE TASFDIEANG KVYVEKGRRI TARHIRQLEK DDIKHIEVPV EYIAGKVAAK DYIDEATGEL ICPANMELSL DLLAKLSQSG HKRIETLFTN DLDHGPYISE TVRVDPTNDR LSALVEIYRM MRPGEPPTRE AAESLFENLF FSEDRYDLSA VGRMKFNRSL LRDEIEGSGI LSKDDIIEVM KKLIDIRNGK GEVDDIDHLG NRRIRSVGEM AENQFRVGLV RVERAVKERL SLGDLDTLMP QDMINAKPIS AAVKEFFGSS QLSQFMDQNN PLSEITHKRR ISALGPGGLT RERAGFEVRD VHPTHYGRVC PIETPEGPNI GLINSLSVYA QTNEYGFLET PYRKVTDGVV TDEIHYLSAI EEGNYVIAQA NSNLDENGHF VEDLVTCRSK GESSLFSRDQ VDYMDVSTQQ VVSVGASLIP FLEHDDANRA LMGANMQRQA VPTLRADKPL VGTGMERAVA VDSGVTAVAK RGGTVQYVDA SRIVIKVNED EMYPGEAGID IYNLTKYTRS NQNTCINQMP CVSLGEPIER GDVLADGPST DLGELALGQN MRVAFMPWNG YNFEDSILVS ERVVQEDRFT TIHIQELACV SRDTKLGPEE ITADIPNVGE AALSKLDESG IVYIGAEVTG GDILVGKVTP KGETQLTPEE KLLRAIFGEK ASDVKDSSLR VPNGVSGTVI DVQVFTRDGV EKDKRALEIE EMQLKQAKKD LSEELQILEA GLFSRIYAVL VSGGVEAEKL DKLPRDRWLE LGLTDEEKQN QLEQLAEQYD ELKHEFEKKL EAKRRKITQG DDLAPGVLKI VKVYLAVKRR IQPGDKMAGR HGNKGVISKI NPIEDMPHDA NGTPVDIVLN PLGVPSRMNI GQILETHLGM AAKGIGDKIN AMLKQQQEVA KLREFIQRAY DLGADVRQKV DLNTFSDEEV LRLAENLRKG MPIATPVFDG AKEAEIKELL QLGDLPTSGQ ITLFDGRTGE QFERPVTVGY MYMLKLNHLV DDKMHARSTG SYSLVTQQPL GGKAQFGGQR FGEMEVWALE AYGAAYTLQE MLTVKSDDVN GRTKMYKNIV DGNHQMEPGM PESFNVLLKE IRSLGINIEL EDE //