ID A6QRH1_HUMAN Unreviewed; 162 AA. AC A6QRH1; DT 21-AUG-2007, integrated into UniProtKB/TrEMBL. DT 21-AUG-2007, sequence version 1. DT 18-SEP-2013, entry version 38. DE SubName: Full=Plexin-B2; DE Flags: Fragment; GN Name=PLXNB2; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=10591208; DOI=10.1038/990031; RA Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., RA Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., RA Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., RA Bird C.P., Blakey S.E., Bridgeman A.M., Buck D., Burgess J., RA Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., RA Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., RA Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., RA Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., RA Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., RA Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., RA Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., RA Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., RA Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., RA Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., RA Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., RA Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., RA Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., RA Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., RA Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., RA Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., RA Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., RA Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., RA Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., RA Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., RA Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., RA Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., RA Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., RA Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., RA Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., RA Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., RA Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., RA Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., RA Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., RA Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., RA Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., RA Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., RA Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., RA Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., RA Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., RA O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., RA Khan A.S., Lane L., Tilahun Y., Wright H.; RT "The DNA sequence of human chromosome 22."; RL Nature 402:489-495(1999). RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (NOV-2012) to UniProtKB. CC -!- SIMILARITY: Contains 1 Sema domain. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL022328; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; BX649592; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CR790389; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CT010163; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR IPI; IPI00941351; -. DR ProteinModelPortal; A6QRH1; -. DR SMR; A6QRH1; 26-161. DR PRIDE; A6QRH1; -. DR Ensembl; ENST00000425954; ENSP00000387470; ENSG00000196576. DR HGNC; HGNC:9104; PLXNB2. DR HOGENOM; HOG000206780; -. DR ChiTaRS; PLXNB2; human. DR NextBio; 35462867; -. DR ArrayExpress; A6QRH1; -. DR Bgee; A6QRH1; -. DR GO; GO:0005887; C:integral to plasma membrane; IEA:Compara. DR GO; GO:0017154; F:semaphorin receptor activity; IEA:Compara. DR GO; GO:0007420; P:brain development; IEA:Compara. DR GO; GO:0001843; P:neural tube closure; IEA:Compara. DR GO; GO:0007405; P:neuroblast proliferation; IEA:Compara. DR GO; GO:0050772; P:positive regulation of axonogenesis; IEA:Compara. DR GO; GO:0008360; P:regulation of cell shape; IEA:Compara. DR GO; GO:2001222; P:regulation of neuron migration; IEA:Compara. DR GO; GO:0001932; P:regulation of protein phosphorylation; IEA:Compara. DR GO; GO:0032319; P:regulation of Rho GTPase activity; IEA:Compara. DR Gene3D; 2.130.10.10; -; 1. DR InterPro; IPR001627; Semap_dom. DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom. DR Pfam; PF01403; Sema; 1. DR SUPFAM; SSF101912; Sema; 1. DR PROSITE; PS51004; SEMA; 1. PE 2: Evidence at transcript level; KW Complete proteome; Reference proteome. FT NON_TER 162 162 SQ SEQUENCE 162 AA; 17414 MW; 020CB580E4AB24C4 CRC64; MALQLWALTL LGLLGAGASL RPRKLDFFRS EKELNHLAVD EASGVVYLGA VNALYQLDAK LQLEQQVATG PALDNKKCTP PIEASQCHEA EMTDNVNQLL LLDPPRKRLV ECGSLFKGIC ALRALSNISL RLFYEDGSGE KSFVASNDEG VATVGLVSST GP //