ID A5D6V9_HUMAN Unreviewed; 406 AA. AC A5D6V9; DT 12-JUN-2007, integrated into UniProtKB/TrEMBL. DT 12-JUN-2007, sequence version 1. DT 04-FEB-2015, entry version 54. DE SubName: Full=CDH23 protein {ECO:0000313|EMBL:AAI39904.1}; GN Name=CDH23 {ECO:0000313|EMBL:AAI39904.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:AAI39904.1}; RN [1] {ECO:0000313|EMBL:AAI39904.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., RA Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., RA Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., RA Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., RA Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., RA Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., RA Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., RA Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., RA Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., RA Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., RA Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., RA Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., RA Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., RA Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., RA Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., RA Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., RA Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., RA Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., RA Makowski K.A., Bosak S., Malek J.; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC139903; AAI39904.1; -; mRNA. DR RefSeq; NP_001165403.1; NM_001171932.1. DR UniGene; Hs.656032; -. DR ProteinModelPortal; A5D6V9; -. DR GeneID; 64072; -. DR KEGG; hsa:64072; -. DR UCSC; uc009xql.3; human. DR CTD; 64072; -. DR PharmGKB; PA26296; -. DR HOGENOM; HOG000139589; -. DR HOVERGEN; HBG099031; -. DR KO; K06813; -. DR ChiTaRS; CDH23; human. DR GenomeRNAi; 64072; -. DR NextBio; 65849; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IEA:InterPro. DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro. DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro. DR Gene3D; 2.60.40.60; -; 4. DR InterPro; IPR002126; Cadherin. DR InterPro; IPR015919; Cadherin-like. DR InterPro; IPR020894; Cadherin_CS. DR Pfam; PF00028; Cadherin; 3. DR PRINTS; PR00205; CADHERIN. DR SMART; SM00112; CA; 3. DR SUPFAM; SSF49313; SSF49313; 3. DR PROSITE; PS00232; CADHERIN_1; 2. DR PROSITE; PS50268; CADHERIN_2; 3. PE 2: Evidence at transcript level; KW Calcium {ECO:0000256|RuleBase:RU000484, KW ECO:0000256|SAAS:SAAS00150335}; KW Cell adhesion {ECO:0000256|SAAS:SAAS00150351}; KW Membrane {ECO:0000256|SAAS:SAAS00150326}; KW Repeat {ECO:0000256|SAAS:SAAS00040979}; KW Transmembrane {ECO:0000256|SAAS:SAAS00150345}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00150337}. SQ SEQUENCE 406 AA; 44521 MW; 9F34253B38118B81 CRC64; MGRHVATSCH VAWLLVLISG CWGQVNRLPF FTNHFFDTYL LISEDTPVGS SVTQLLAQDM DNDPLVFGVS GEEASRFFAV EPDTGVVWLR QPLDRETKSE FTVEFSVSDH QGVITRKVNI QVGDVNDNAP TFHNQPYSVR IPENTPVGTP IFIVNATDPD LGAGGSVLYS FQPPSQFFAI DSARGIVTVI RELDYETTQA YQLTVNATDQ DKTRPLSTLA NLAIIITDVQ DMDPIFINLP YSTNIYEHSP PGTTVRIITA IDQDKGRPRG IGYTIVSGNT NSIFALDYIS GVLTLNGLLD RENPLYSHGF ILTVKGTELN DDRTPSDATV TTTFNILVID INDNAPEFNS SEYSVAITEL AQVGFALPLF IQVVDKDEVS PWTHGPCRPT THPDPPPCLG CSGPQL //