ID A4Z7J7_HUMAN Unreviewed; 290 AA. AC A4Z7J7; DT 29-MAY-2007, integrated into UniProtKB/TrEMBL. DT 29-MAY-2007, sequence version 1. DT 03-AUG-2022, entry version 55. DE RecName: Full=Arylamine N-acetyltransferase {ECO:0000256|ARBA:ARBA00012701}; DE EC=2.3.1.5 {ECO:0000256|ARBA:ARBA00012701}; GN Name=NAT2 {ECO:0000313|EMBL:ABF01396.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:ABF01396.1}; RN [1] {ECO:0000313|EMBL:ABF01396.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=CHAGGA4152-1 {ECO:0000313|EMBL:ABF01396.1}, and SAN1029-1 RC {ECO:0000313|EMBL:ABF01558.1}; RA Patin E., Harmant C., Quintana-Murci L.; RT "Sub-Saharan African coding sequence variation and haplotype diversity at RT the NAT2 gene."; RL Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the arylamine N-acetyltransferase family. CC {ECO:0000256|ARBA:ARBA00006547, ECO:0000256|RuleBase:RU003452}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DQ472998; ABF01396.1; -; Genomic_DNA. DR EMBL; DQ473160; ABF01558.1; -; Genomic_DNA. DR SMR; A4Z7J7; -. DR PRIDE; A4Z7J7; -. DR ChiTaRS; NAT2; human. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0004060; F:arylamine N-acetyltransferase activity; IEA:UniProtKB-EC. DR InterPro; IPR001447; Arylamine_N-AcTrfase. DR InterPro; IPR038765; Papain-like_cys_pep_sf. DR PANTHER; PTHR11786; PTHR11786; 1. DR Pfam; PF00797; Acetyltransf_2; 1. DR PRINTS; PR01543; ANATRNSFRASE. DR SUPFAM; SSF54001; SSF54001; 1. PE 3: Inferred from homology; KW Acyltransferase {ECO:0000256|RuleBase:RU003452}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Transferase {ECO:0000256|RuleBase:RU003452, ECO:0000313|EMBL:ABF01396.1}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 74..95 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" SQ SEQUENCE 290 AA; 33643 MW; FAEE3BC2131F000E CRC64; MDIEAYFERI GYKNSRNKLD LETLTDILEH QIRAVPFENL NMHCGQAMEL GLEAIFDHIV RRNRGGWCLQ VNQLLYWALT TIGFQTTMLG GYFYIPPVNK YSTGMVHLLL QVTIDGRNYI VDAGSGSSSQ MWQPLELISG KDQPQVPCIF CLTEERGIWY LDQIRREQYI TNKEFLNSHL LPKKKHQKIY LFTLEPRTIE DFESMNTYLQ TSPTSSFITT SFCSLQTPEG VYCLVGFILT YRKFNYKDNT DLVEFKTLTE EEVEEVLRNI FKISLGRNLV PKPGDESLTI //