ID DEF2_PINSY Reviewed; 83 AA. AC A4L7R8; DT 23-MAR-2010, integrated into UniProtKB/Swiss-Prot. DT 01-MAY-2007, sequence version 1. DT 15-JUN-2010, entry version 9. DE RecName: Full=Defensin-2; DE Flags: Precursor; GN Name=Def2; OS Pinus sylvestris (Scots pine). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Coniferopsida; Coniferales; Pinaceae; Pinus; Pinus. OX NCBI_TaxID=3349; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA]. RC TISSUE=Root; RX PubMed=19253756; RA Koval'ova V.A., Hut R.T.; RT "Molecular cloning and characterization of Scotch pine Defensin-2."; RL Cyt. Genet. 42:55-60(2008). CC -!- FUNCTION: Plant defense peptide. Has antifungal activity. CC -!- SUBCELLULAR LOCATION: Secreted (By similarity). CC -!- SIMILARITY: Belongs to the DEFL family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EF455617; ABO61349.1; -; mRNA. DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW. DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW. DR InterPro; IPR008177; G_Purothionin. DR InterPro; IPR008176; Gamma-thionin. DR InterPro; IPR003614; Knot1. DR Pfam; PF00304; Gamma-thionin; 1. DR PRINTS; PR00288; PUROTHIONIN. DR SMART; SM00505; Knot1; 1. DR PROSITE; PS00940; GAMMA_THIONIN; 1. PE 3: Inferred from homology; KW Antimicrobial; Defensin; Disulfide bond; Fungicide; Secreted; Signal. FT SIGNAL 1 33 Potential. FT CHAIN 34 83 Defensin-2. FT /FTId=PRO_0000392922. FT DISULFID 36 82 By similarity. FT DISULFID 47 67 By similarity. FT DISULFID 53 76 By similarity. FT DISULFID 57 78 By similarity. SQ SEQUENCE 83 AA; 8963 MW; CE44E1A01E3731B6 CRC64; MAGKGVGTPL SALFLLVLLV VTIGMMEVQV AEGRMCKTPS AKFKGYCVSS TNCKNVCRTE GFPTGSCDFH ITSRKCYCYK PCP //