ID   A4J2B3_DESRM            Unreviewed;       303 AA.
AC   A4J2B3;
DT   01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2007, sequence version 1.
DT   05-FEB-2008, entry version 9.
DE   UDP-N-acetylmuramate dehydrogenase (EC 1.1.1.158).
GN   ORFNames=Dred_0677;
OS   Desulfotomaculum reducens (strain MI-1).
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Peptococcaceae;
OC   Desulfotomaculum.
OX   NCBI_TaxID=349161;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=MI-1;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Sims D., Brettin T., Bruce D., Han C., Tapia R.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA   Tebo B.M., Richardson P.;
RT   "Complete sequence of Desulfotomaculum reducens MI-1.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Cell wall formation (By similarity).
CC   -!- CATALYTIC ACTIVITY: UDP-N-acetylmuramate + NADP(+) = UDP-N-acetyl-
CC       3-O-(1-carboxyvinyl)-D-glucosamine + NADPH.
CC   -!- COFACTOR: FAD (By similarity).
CC   -!- PATHWAY: Cell wall biosynthesis; peptidoglycan biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
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DR   EMBL; CP000612; ABO49216.1; -; Genomic_DNA.
DR   RefSeq; YP_001112041.1; -.
DR   GeneID; 4956648; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0050660; F:FAD binding; IEA:InterPro.
DR   GO; GO:0008762; F:UDP-N-acetylmuramate dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   InterPro; IPR003170; MurB.
DR   InterPro; IPR011601; MurB_C.
DR   InterPro; IPR006094; Oxid_FAD_bind_N.
DR   Gene3D; G3DSA:3.90.78.10; MurB_C; 1.
DR   PANTHER; PTHR21071; MurB; 1.
DR   Pfam; PF01565; FAD_binding_4; 1.
DR   Pfam; PF02873; MurB_C; 1.
DR   TIGRFAMs; TIGR00179; murB; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell shape;
KW   Cell wall biogenesis/degradation; Cytoplasm; FAD; Flavoprotein; NADP;
KW   Oxidoreductase; Peptidoglycan synthesis.
SQ   SEQUENCE   303 AA;  32593 MW;  07AA6525BDA3E7D3 CRC64;
     MIYTSLAGEL QSLVKGSIQI NEPMRKHTTW KIGGKADLFL NPSDKEDIRQ AVEFAREKAI
     PITVIGNGSN LLVKDGGIRG LVIKVGRGMA KITIEGTSIK AGAGALLPEL AVFACKNSLG
     GFGFAAGIPG SLGGAIVMNA GAMNGCVSDV LQSIVVLNER NQFEVLTKDH LNFAYRTSNL
     QSRGLICVET CWQGYAKDQW LIEQETKEYL AKRKAAQPQG FPNAGSVFKN PEGDFAGRLI
     EGCGGKGLRV GDAEVSSKHA NWILNLGRAT AQDVLILIDH LKQMVQERFG VLLQLEVKVL
     GED
//