ID   A4H449_LEIBR            Unreviewed;       195 AA.
AC   A4H449;
DT   01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2007, sequence version 1.
DT   05-FEB-2008, entry version 8.
DE   Small GTP-binding protein, putative.
GN   ORFNames=LbrM05_V2.0030;
OS   Leishmania braziliensis.
OC   Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Leishmania;
OC   Leishmania braziliensis species complex.
OX   NCBI_TaxID=5660;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=MHOM/BR/75/M2904;
RX   PubMed=17572675; DOI=10.1038/ng2053;
RA   Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA   Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA   Fraser A., Rajandream M.A., Carver T., Norbertczak H.,
RA   Chillingworth T., Hance Z., Jagels K., Moule S., Ormond D., Rutter S.,
RA   Sqaures R., Whitehead S., Rabbinowitsch E., Arrowsmith C., White B.,
RA   Thurston S., Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D.,
RA   Depledge D.P., Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R.,
RA   Barrell B., Cruz A.K., Mottram J.C., Smith D.F., Berriman M.;
RT   "Comparative genomic analysis of three Leishmania species that cause
RT   diverse human disease.";
RL   Nat. Genet. 39:839-847(2007).
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily.
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. SAR1 family.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AM494942; CAM36837.1; -; Genomic_DNA.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR   InterPro; IPR001412; aa-tRNA-synth_I.
DR   InterPro; IPR006689; ARF/SAR.
DR   InterPro; IPR001806; Ras_trnsfrmng.
DR   InterPro; IPR006687; SAR1_GTP_bd.
DR   InterPro; IPR005225; Small_GTP_bd.
DR   PANTHER; PTHR11711; ARF/SAR; 1.
DR   PANTHER; PTHR11711:SF12; SAR1_GTP_bd; 1.
DR   Pfam; PF00025; Arf; 1.
DR   PRINTS; PR00449; RASTRNSFRMNG.
DR   PRINTS; PR00328; SAR1GTPBP.
DR   SMART; SM00178; SAR; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS00178; AA_TRNA_LIGASE_I; UNKNOWN_1.
PE   3: Inferred from homology;
KW   ER-Golgi transport; Endoplasmic reticulum; GTP-binding;
KW   Golgi apparatus; Nucleotide-binding; Protein transport; Transport.
SQ   SEQUENCE   195 AA;  21702 MW;  7C69D8EF74BDADFA CRC64;
     MGWLTWFWDW LSYLGLSNKT GKLLFLGLDN AGKTTLLGKL ATNQVHVHRP TFHPNSEDLT
     LGGIKLKTID MGGHQQARRL WKDYFTKVDG VVFIVDAATP QRFPEAKSEL DMLLQSEELA
     KTPFLILGNK IDMPGCTCSE AQLVMEMGLG GALTGKSTTV TDPNVRPLEV YMCSVVKNVG
     YGDGFRWLSR YLKSS
//