ID   A4GWZ1_HUMAN            Unreviewed;       273 AA.
AC   A4GWZ1;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   07-JAN-2015, entry version 44.
DE   SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABO21859.1};
DE   Flags: Fragment;
GN   Name=HLA-A {ECO:0000313|EMBL:ABO21859.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:ABO21859.1};
RN   [1] {ECO:0000313|EMBL:ABO21859.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Hong S.A., Lee J.S., Kwon O.J.;
RT   "A novel HLA-A*24 allele.";
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABO21859.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=18201363; DOI=10.1111/j.1399-0039.2007.00988.x;
RA   Kwon O.J., Oh Y., Oh J.W., Seo K.H., Park C.;
RT   "A new HLA-A*24 variant, A*2475, identified by sequence-based typing
RT   in the Korean population.";
RL   Tissue Antigens 71:175-176(2008).
CC   -!- SIMILARITY: Belongs to the MHC class I family.
CC       {ECO:0000256|RuleBase:RU004439}.
CC   -!- SIMILARITY: Contains Ig-like C1-type (immunoglobulin-like) domain.
CC       {ECO:0000256|SAAS:SAAS00096055}.
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DR   EMBL; EF447433; ABO21859.1; -; Genomic_DNA.
DR   ProteinModelPortal; A4GWZ1; -.
DR   PRIDE; A4GWZ1; -.
DR   HOVERGEN; HBG016709; -.
DR   ChiTaRS; HLA-A; human.
DR   NextBio; 35461798; -.
DR   GO; GO:0042612; C:MHC class I protein complex; IEA:InterPro.
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 1.
DR   Gene3D; 3.30.500.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003006; Ig/MHC_CS.
DR   InterPro; IPR003597; Ig_C1-set.
DR   InterPro; IPR011161; MHC_I-like_Ag-recog.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   InterPro; IPR027648; MHC_I_a.
DR   InterPro; IPR001039; MHC_I_a_a1/a2.
DR   Pfam; PF07654; C1-set; 1.
DR   Pfam; PF00129; MHC_I; 1.
DR   PRINTS; PR01638; MHCCLASSI.
DR   SMART; SM00407; IGc1; 1.
DR   SUPFAM; SSF54452; SSF54452; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
DR   PROSITE; PS00290; IG_MHC; 1.
PE   3: Inferred from homology;
FT   NON_TER       1      1       {ECO:0000313|EMBL:ABO21859.1}.
FT   NON_TER     273    273       {ECO:0000313|EMBL:ABO21859.1}.
SQ   SEQUENCE   273 AA;  31494 MW;  A05427B2729D549B CRC64;
     SHSMRYFSTS VSRPGRGEPR FIAVGYVDDT QFVRFDSDAA SQRMEPRAPW IEQEGPEYWD
     EETGKVKAHS QTDRENLRIA LRYYNQSEAG SHTLQMMFGC DVGSDGRFLR GYHQYAYDGK
     DYIALKEDLR SWTAADMAAQ ITKRKWEAAH VAEQQRAYLE GTCVDGRRRY LENGKETLQR
     TDPPKTHMTH HPISDHEATL RCWALGFYPA EITLTWQRDG EDQTQDTELV ETRPAGDGTF
     QKWAAVVVPS GEEQRYTCHV QHEGLPKPLT LRW
//