ID A4FV12_BOVIN Unreviewed; 640 AA. AC A4FV12; DT 17-APR-2007, integrated into UniProtKB/TrEMBL. DT 17-APR-2007, sequence version 1. DT 27-JUL-2011, entry version 33. DE SubName: Full=UBA2 protein; DE SubName: Full=Uncharacterized protein; GN Name=UBA2; OS Bos taurus (Bovine). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; OC Pecora; Bovidae; Bovinae; Bos. OX NCBI_TaxID=9913; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Hereford; RX PubMed=19390049; DOI=10.1126/science.1169588; RG The bovine genome sequencing and analysis consortium; RT "The genome sequence of taurine cattle: a window to ruminant biology RT and evolution."; RL Science 324:522-528(2009). RN [2] RP IDENTIFICATION. RC STRAIN=Hereford; RG Ensembl; RL Submitted (JUN-2011) to UniProtKB. RN [3] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Hereford; TISSUE=Fetal lung; RA Moore S., Alexander L., Brownstein M., Guan L., Lobo S., Meng Y., RA Tanaguchi M., Wang Z., Yu J., Prange C., Schreiber K., Shenmen C., RA Wagner L., Bala M., Barbazuk S., Barber S., Babakaiff R., Beland J., RA Chun E., Del Rio L., Gibson S., Hanson R., Kirkpatrick R., Liu J., RA Matsuo C., Mayo M., Santos R.R., Stott J., Tsai M., Wong D., RA Siddiqui A., Holt R., Jones S.J., Marra M.A.; RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the ubiquitin-activating E1 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AAFC03026780; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; BC123590; AAI23591.1; -; mRNA. DR IPI; IPI00685422; -. DR RefSeq; NP_001076850.1; NM_001083381.1. DR UniGene; Bt.13185; -. DR ProteinModelPortal; A4FV12; -. DR SMR; A4FV12; 4-550. DR STRING; A4FV12; -. DR PRIDE; A4FV12; -. DR Ensembl; ENSBTAT00000003333; ENSBTAP00000003333; ENSBTAG00000002573. DR GeneID; 507005; -. DR KEGG; bta:507005; -. DR CTD; 507005; -. DR eggNOG; maNOG09123; -. DR GeneTree; ENSGT00550000074924; -. DR HOVERGEN; HBG060266; -. DR InParanoid; A4FV12; -. DR OMA; WEPMEAE; -. DR OrthoDB; EOG4PRSQ8; -. DR PhylomeDB; A4FV12; -. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW. DR InterPro; IPR009036; Molybdenum_cofac_synth_MoeB. DR InterPro; IPR016040; NAD(P)-bd_dom. DR InterPro; IPR000594; ThiF_NAD_FAD-bd. DR InterPro; IPR023280; Ub-like_act_enz_cat_cys_dom. DR InterPro; IPR000127; UBact_repeat. DR InterPro; IPR019572; Ubiquitin-activating_enzyme. DR InterPro; IPR018074; UBQ-activ_enz_E1_AS. DR Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 2. DR Gene3D; G3DSA:1.10.3240.10; Ub-like_act_enz_cat_cys_dom; 1. DR Pfam; PF00899; ThiF; 1. DR Pfam; PF10585; UBA_e1_thiolCys; 1. DR Pfam; PF02134; UBACT; 1. DR SUPFAM; SSF69572; MoeB; 1. DR PROSITE; PS00536; UBIQUITIN_ACTIVAT_1; 1. DR PROSITE; PS00865; UBIQUITIN_ACTIVAT_2; 1. PE 2: Evidence at transcript level; KW ATP-binding; Complete proteome; Ligase; Nucleotide-binding; KW Ubl conjugation pathway. SQ SEQUENCE 640 AA; 71031 MW; 4B1946642E4AE5DA CRC64; MALSRGLPRE LAEAVAGGRV LVVGAGGIGC ELLKNLVLTG FSHIDLIDLD TIDVSNLNRQ FLFQKKHVGR SKAQVAKESV LQFYPKANIV AYHDSIMNPD YNVEFFRQFI LVMNALDNRA ARNHVNRMCL AADVPLIESG TAGYLGQVTT IKKGVTECYE CHPKPTQRTF PGCTIRNTPS EPIHCIVWAK YLFNQLFGEE DADQEVSPDR ADPEASWEPM EAEARARASN EDGDIKRVST KEWAKSTGYD PVKLFTKLFK DDIRYLLTMD KLWRKRKPPV PLDWAEVQSQ GEETSASDQQ NEPQLGLKDQ QVLDVKSYAC LFSKSIETLR VHLAEKGDGA ELIWDKDDPS AMDFVTSAAN LRMHIFSMNM KSRFDIKSMA GNIIPAIATT NAVIAGLIVL EGLKILSGKI DQCRTIFLNK QPNPRKKLLV PCALDAPNPN CYVCASKPEV TVRLNVHKVT VLTLQDKIVK EKFAMVAPDV QIEDGKGTIL ISSEEGETEA NNHKKLSEFG IRNGSRLQAD DFLQDYTLLI NILHSEDLGK DVEFEVVGDA PEKVGPKQAE DAAKSITNGS DDGAQPSTST AQEQDDVLIV DSDEEGPSNN ADISEEERSR KRKLDEKESV SAKRSRIEQA EELDEVIALD //