ID   A3PJQ3_RHOS1            Unreviewed;       225 AA.
AC   A3PJQ3;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   03-APR-2007, sequence version 1.
DT   10-JUL-2007, entry version 4.
DE   2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
DE   (EC 2.7.7.60).
GN   OrderedLocusNames=Rsph17029_1459;
OS   Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Rhodobacter.
OX   NCBI_TaxID=349101;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Richardson P., Mackenzie C., Choudhary M.,
RA   Donohue T.J., Kaplan S.;
RT   "Complete sequence of chromosome 1 of Rhodobacter sphaeroides ATCC
RT   17029.";
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the formation of 4-diphosphocytidyl-2-C-
CC       methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-
CC       phosphate (MEP) (By similarity).
CC   -!- CATALYTIC ACTIVITY: CTP + 2-C-methyl-D-erythritol 4-phosphate =
CC       diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol.
CC   -!- PATHWAY: Isoprenoid biosynthesis; isopentenyl-PP biosynthesis via
CC       DXP pathway; isopentenyl-PP from 1-deoxy-D-xylulose 5-phosphate:
CC       step 2.
CC   -!- SIMILARITY: Belongs to the ispD family.
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DR   EMBL; CP000577; ABN76569.1; -; Genomic_DNA.
DR   InterPro; IPR001228; ISPD_synthase.
DR   Pfam; PF01128; IspD; 1.
DR   TIGRFAMs; TIGR00453; ispD; 1.
DR   PROSITE; PS01295; ISPD; 1.
KW   Complete proteome; Isoprene biosynthesis; Nucleotidyltransferase;
KW   Transferase.
SQ   SEQUENCE   225 AA;  23026 MW;  04558F8E98AA89FE CRC64;
     MTTAAIIVAA GRGTRAGGDL PKQWQPLAGR PVLAHTLAAF RAAAGVSRTL LVIHPDDRAR
     AEALPGVAEG KVELVEGGAS RDASVRNALE ALAGAGIERV LIHDGARPLV APGLIARTLA
     ALETAPGAAP AVPVSDALWR GEGGRVVGTQ DRTGLFRAQT PQAFRYEAIL AAHRAHPGGA
     ADDVEVARAA GLEVAIVEGC EDNLKVTYPG DFARAERLLA LAAGL
//