ID LCL2_PICST Reviewed; 133 AA. AC A3LY18; DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot. DT 03-APR-2007, sequence version 1. DT 26-FEB-2020, entry version 47. DE RecName: Full=Long chronological lifespan protein 2; DE Flags: Precursor; GN Name=LCL2; ORFNames=PICST_48963; OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL OS Y-11545) (Yeast) (Pichia stipitis). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces. OX NCBI_TaxID=322104; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545; RX PubMed=17334359; DOI=10.1038/nbt1290; RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A., RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S., RA Passoth V., Richardson P.M.; RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting RT yeast Pichia stipitis."; RL Nat. Biotechnol. 25:319-326(2007). CC -!- FUNCTION: Probable component of the endoplasmic reticulum-associated CC degradation (ERAD) pathway. {ECO:0000250}. CC -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000500; ABN67558.1; -; Genomic_DNA. DR RefSeq; XP_001385587.1; XM_001385550.1. DR STRING; 4924.XP_001385587.1; -. DR EnsemblFungi; ABN67558; ABN67558; PICST_48963. DR GeneID; 4839859; -. DR KEGG; pic:PICST_48963; -. DR eggNOG; ENOG410J0W8; Eukaryota. DR eggNOG; ENOG41123H3; LUCA. DR HOGENOM; CLU_142363_1_0_1; -. DR InParanoid; A3LY18; -. DR OMA; YICISKP; -. DR OrthoDB; 1618788at2759; -. DR Proteomes; UP000002258; Chromosome 6. DR InterPro; IPR034543; LCL2. DR PANTHER; PTHR38425; PTHR38425; 1. PE 3: Inferred from homology; KW Reference proteome; Signal. FT SIGNAL 1..17 FT /evidence="ECO:0000255" FT CHAIN 18..133 FT /note="Long chronological lifespan protein 2" FT /id="PRO_0000408623" SQ SEQUENCE 133 AA; 14837 MW; 1892D8978C310959 CRC64; MIRVISLFLV FVSLASANIF DFLNNNFAGR GQQQGGQVQT PEQYENAILN TNCGKYVCPD TGMCVEAPKF CPCPYPSSQL RCFLPDGRYL CISKPAGDIS AKYDDPKSNW KVDAKDDNIR DCGWVSRAWR GLV //