ID A2TDY8_DROSI Unreviewed; 284 AA. AC A2TDY8; DT 06-MAR-2007, integrated into UniProtKB/TrEMBL. DT 06-MAR-2007, sequence version 1. DT 27-MAR-2024, entry version 63. DE SubName: Full=Mitochondrial cytochrome c oxidase subunit 6A isoform 2 {ECO:0000313|EMBL:ABM88322.1}; GN Name=COX6A-2 {ECO:0000313|EMBL:ABM88322.1}; OS Drosophila simulans (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; OC Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7240 {ECO:0000313|EMBL:ABM88322.1}; RN [1] {ECO:0000313|EMBL:ABM88322.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=3-KY0414 {ECO:0000313|EMBL:ABM88322.1}; RX PubMed=17598752; DOI=10.1111/j.1558-5646.2007.00133.x; RA Ballard J.W., Melvin R.G., Katewa S.D., Maas K.; RT "Mitochondrial DNA variation is associated with measurable differences in RT life-history traits and mitochondrial metabolism in Drosophila simulans."; RL Evolution 61:1735-1747(2007). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EF189544; ABM88322.1; -; Genomic_DNA. DR AlphaFoldDB; A2TDY8; -. DR GO; GO:0005751; C:mitochondrial respiratory chain complex IV; IEA:InterPro. DR CDD; cd00925; Cyt_c_Oxidase_VIa; 1. DR Gene3D; 4.10.95.10; Cytochrome c oxidase, subunit VIa; 1. DR InterPro; IPR001349; Cyt_c_oxidase_su6a. DR InterPro; IPR036418; Cyt_c_oxidase_su6a_sf. DR PANTHER; PTHR11504; CYTOCHROME C OXIDASE POLYPEPTIDE VIA; 1. DR PANTHER; PTHR11504:SF0; CYTOCHROME C OXIDASE SUBUNIT 6A-LIKE-RELATED; 1. DR SUPFAM; SSF81411; Mitochondrial cytochrome c oxidase subunit VIa; 1. PE 4: Predicted; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128}; KW Transit peptide {ECO:0000256|ARBA:ARBA00022946}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 155..176 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT REGION 26..91 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 224..284 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 34..80 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 233..284 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 284 AA; 31701 MW; 60DC236ED0978FFE CRC64; MRHLQLMKYV NPRFAINTII TQRLMSKSDG KSSGTGSKDA KCKDTKDAAK KSSDPKAKAS DAAKKATPPK AAKETKVTPP KDETAISGGS KCPPKVSCVA ETNKNKKKKQ SCDELLSGKS TRKQKKPLTA IQGGDLGCPG RTGKKPPIVA QHAKVWQKIS LFGVLPMIAI LTLLVFSTRS EEERLEFKNY EHMYRRTKRY WFKDGNRTAF HNSHFNALPP AGYEDEVDES GIGQEPETVK DKKARMKEFD KVVKNWRKHS SKRDAQLKKE AAAAEKEARK QEAQ //