ID A2PZ70_CRYJA Unreviewed; 316 AA. AC A2PZ70; DT 06-MAR-2007, integrated into UniProtKB/TrEMBL. DT 06-MAR-2007, sequence version 1. DT 16-DEC-2008, entry version 16. DE RecName: Full=S-adenosylmethionine synthetase; DE EC=2.5.1.6; DE Flags: Fragment; GN Name=CC2188; OS Cryptomeria japonica (Japanese cedar). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Coniferopsida; Coniferales; Cupressaceae; Cryptomeria. OX NCBI_TaxID=3369; RN [1] RP NUCLEOTIDE SEQUENCE. RA Kado T., Matsumoto A., Ujino-Ihara T., Tsumura Y.; RT "Amounts and patterns of nucleotide variation within and between two RT Japanese conifers, sugi (Cryptomeria japonica) and hinoki RT (Chamaecyparis obtusa) (Cupressaceae sensu lato)."; RL Tree Genet. Genomes 4:133-141(2008). CC -!- FUNCTION: Catalyzes the formation of S-adenosylmethionine from CC methionine and ATP (By similarity). CC -!- CATALYTIC ACTIVITY: ATP + L-methionine + H(2)O = phosphate + CC diphosphate + S-adenosyl-L-methionine. CC -!- COFACTOR: Binds 1 potassium ion per subunit (By similarity). CC -!- COFACTOR: Binds 2 divalent ions per subunit. Magnesium or cobalt CC (By similarity). CC -!- PATHWAY: Activated methyl cycle. CC -!- SIMILARITY: Belongs to the AdoMet synthetase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB264254; BAF46024.1; -; Genomic_DNA. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-KW. DR GO; GO:0004478; F:methionine adenosyltransferase activity; IEA:InterPro. DR GO; GO:0030955; F:potassium ion binding; IEA:UniProtKB-KW. DR GO; GO:0006730; P:one-carbon compound metabolic process; IEA:InterPro. DR InterPro; IPR002133; S-AdoMet_synthetase. DR PANTHER; PTHR11964; S-AdoMet_synt; 1. DR Pfam; PF02773; S-AdoMet_synt_C; 1. DR Pfam; PF02772; S-AdoMet_synt_M; 1. DR Pfam; PF00438; S-AdoMet_synt_N; 1. DR TIGRFAMs; TIGR01034; metK; 1. DR PROSITE; PS00376; ADOMET_SYNTHETASE_1; 1. DR PROSITE; PS00377; ADOMET_SYNTHETASE_2; 1. PE 3: Inferred from homology; FT NON_TER 1 1 FT NON_TER 316 316 SQ SEQUENCE 316 AA; 34426 MW; 7D4A34726149791F CRC64; VRKTCREIGF ISDDVGLDAD KCRVLVNIEQ QSPDIAQGVH GHLTKRPEDI GAGDQGHMFG YATDETPELM PLTHVLATKL GAKLTDVRKN GTCPWLRPDG KTQVTIEYKN EKGAMVPLRV HTVLISTQHD ETVTNDQIAA DLKEHVIKPV IPAKYMDENT IFHLNPSGRF VIGGPHGDAG LTGRKIIIDT YGGWGAHGGG AFSGKDPTKV DRSGAYIVRQ AAKSIVAAGL ARRCIVQVSY AIGVPEPLSV FVDSYGTGKI PDKEILNIIK TSFDFRPGMI SINLDLKRGG NGRFQKTAAY GHFGRDDPDF TWEIVK //