ID A2C604_PROM3 Unreviewed; 135 AA. AC A2C604; DT 20-FEB-2007, integrated into UniProtKB/TrEMBL. DT 20-FEB-2007, sequence version 1. DT 16-APR-2014, entry version 44. DE RecName: Full=Putative fluoride ion transporter CrcB; GN Name=crcB; OrderedLocusNames=P9303_01591; OS Prochlorococcus marinus (strain MIT 9303). OC Bacteria; Cyanobacteria; Prochlorales; Prochlorococcaceae; OC Prochlorococcus. OX NCBI_TaxID=59922; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MIT 9303; RX PubMed=18159947; DOI=10.1371/journal.pgen.0030231; RA Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., RA Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., RA Steglich C., Church G.M., Richardson P., Chisholm S.W.; RT "Patterns and implications of gene gain and loss in the evolution of RT Prochlorococcus."; RL PLoS Genet. 3:2515-2528(2007). CC -!- FUNCTION: Important for reducing fluoride concentration in the CC cell, thus reducing its toxicity (By similarity). CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane CC protein (By similarity). CC -!- SIMILARITY: Belongs to the CrcB (TC 9.B.71) family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000554; ABM76914.1; -; Genomic_DNA. DR RefSeq; YP_001016179.1; NC_008820.1. DR STRING; 59922.P9303_01591; -. DR EnsemblBacteria; ABM76914; ABM76914; P9303_01591. DR GeneID; 4776693; -. DR KEGG; pmf:P9303_01591; -. DR PATRIC; 22997668; VBIProMar17757_0165. DR eggNOG; NOG134700; -. DR HOGENOM; HOG000052573; -. DR KO; K06199; -. DR OMA; HWGTFAV; -. DR OrthoDB; EOG6091KP; -. DR ProtClustDB; CLSK825827; -. DR BioCyc; PMAR59922:GH54-211-MONOMER; -. DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-HAMAP. DR GO; GO:0015103; F:inorganic anion transmembrane transporter activity; IEA:UniProtKB-HAMAP. DR HAMAP; MF_00454; CrcB; 1. DR InterPro; IPR003691; CrcB. DR Pfam; PF02537; CRCB; 1. PE 3: Inferred from homology; KW Cell inner membrane; Cell membrane; Complete proteome; Membrane; KW Transmembrane; Transmembrane helix; Transport. FT TRANSMEM 8 28 Helical; (By similarity). FT TRANSMEM 44 64 Helical; (By similarity). FT TRANSMEM 77 97 Helical; (By similarity). FT TRANSMEM 112 132 Helical; (By similarity). SQ SEQUENCE 135 AA; 13803 MW; 3E9CE0E61D1D9A5C CRC64; MAGSMSDLAL PAWQASLVAI GAVPGAWLRL RVVNHLEPMV PRKHWGTFAV NMVAAFALGL VLALQAKCAP ASGASPLILL IGVGFFGSLS TFSTFAGEVL NTLREHRWSE ALVLAVGSIL GGLLAVAAGV GLADG //