ID A2C233_PROM1 Unreviewed; 666 AA. AC A2C233; DT 20-FEB-2007, integrated into UniProtKB/TrEMBL. DT 20-FEB-2007, sequence version 1. DT 02-NOV-2016, entry version 69. DE RecName: Full=Chaperone protein DnaK {ECO:0000256|HAMAP-Rule:MF_00332}; DE AltName: Full=HSP70 {ECO:0000256|HAMAP-Rule:MF_00332}; DE AltName: Full=Heat shock 70 kDa protein {ECO:0000256|HAMAP-Rule:MF_00332}; DE AltName: Full=Heat shock protein 70 {ECO:0000256|HAMAP-Rule:MF_00332}; GN Name=dnaK {ECO:0000256|HAMAP-Rule:MF_00332}; GN OrderedLocusNames=NATL1_09851 {ECO:0000313|EMBL:ABM75543.1}; OS Prochlorococcus marinus (strain NATL1A). OC Bacteria; Cyanobacteria; Synechococcales; Prochloraceae; OC Prochlorococcus. OX NCBI_TaxID=167555 {ECO:0000313|EMBL:ABM75543.1, ECO:0000313|Proteomes:UP000002592}; RN [1] {ECO:0000313|Proteomes:UP000002592} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=NATL1A {ECO:0000313|Proteomes:UP000002592}; RX PubMed=18159947; DOI=10.1371/journal.pgen.0030231; RA Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., RA Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., RA Steglich C., Church G.M., Richardson P., Chisholm S.W.; RT "Patterns and implications of gene gain and loss in the evolution of RT Prochlorococcus."; RL PLoS Genet. 3:2515-2528(2007). CC -!- FUNCTION: Acts as a chaperone. {ECO:0000256|HAMAP-Rule:MF_00332}. CC -!- INDUCTION: By stress conditions e.g. heat shock. CC {ECO:0000256|HAMAP-Rule:MF_00332}. CC -!- SIMILARITY: Belongs to the heat shock protein 70 family. CC {ECO:0000256|HAMAP-Rule:MF_00332, ECO:0000256|RuleBase:RU003322}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000553; ABM75543.1; -; Genomic_DNA. DR RefSeq; WP_011823669.1; NC_008819.1. DR ProteinModelPortal; A2C233; -. DR STRING; 167555.NATL1_09851; -. DR EnsemblBacteria; ABM75543; ABM75543; NATL1_09851. DR KEGG; pme:NATL1_09851; -. DR PATRIC; 23019565; VBIProMar31285_1009. DR eggNOG; ENOG4108KBA; Bacteria. DR eggNOG; COG0443; LUCA. DR HOGENOM; HOG000228135; -. DR KO; K04043; -. DR OMA; CQSVNPD; -. DR OrthoDB; POG091H01UE; -. DR Proteomes; UP000002592; Chromosome. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP. DR GO; GO:0006457; P:protein folding; IEA:InterPro. DR Gene3D; 1.20.1270.10; -; 1. DR Gene3D; 2.60.34.10; -; 1. DR HAMAP; MF_00332; DnaK; 1. DR InterPro; IPR012725; Chaperone_DnaK. DR InterPro; IPR018181; Heat_shock_70_CS. DR InterPro; IPR029048; HSP70_C. DR InterPro; IPR029047; HSP70_peptide-bd. DR InterPro; IPR013126; Hsp_70_fam. DR Pfam; PF00012; HSP70; 1. DR PRINTS; PR00301; HEATSHOCK70. DR SUPFAM; SSF100920; SSF100920; 1. DR PROSITE; PS00297; HSP70_1; 1. DR PROSITE; PS00329; HSP70_2; 1. DR PROSITE; PS01036; HSP70_3; 1. PE 2: Evidence at transcript level; KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_00332, KW ECO:0000256|RuleBase:RU003322}; KW Chaperone {ECO:0000256|HAMAP-Rule:MF_00332}; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000002592}; KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00332, KW ECO:0000256|RuleBase:RU003322}; KW Phosphoprotein {ECO:0000256|HAMAP-Rule:MF_00332}; KW Stress response {ECO:0000256|HAMAP-Rule:MF_00332, KW ECO:0000313|EMBL:ABM75543.1}. FT COILED 244 274 {ECO:0000256|SAM:Coils}. FT MOD_RES 198 198 Phosphothreonine; by autocatalysis. FT {ECO:0000256|HAMAP-Rule:MF_00332}. SQ SEQUENCE 666 AA; 73186 MW; 9E1697B8D71E03A5 CRC64; MGRIVGIDLG TTNSVVAVLE AGRPVVIASA EGARTTPSVV GFTKESELLV GQLARRQLVL NPKNTFSNLK RFVGRAWDEL EETSLSVPYS VRSNDQGNVR ITSPITKREY APEELIGNII RKLIDDAETY LGENVDAAVI TVPAYFNDSQ RQATRDAAIL AGISVERILN EPTSAALAYG FDKSSSRKVL VFDLGGGTFD VSLMSISNGV FDVKATSGDT QLGGNDFDQR IVDWLAEDFL AKNKLDLRRD RQSLQRLTEA AEKAKQELSG VQATPISLPF ISTGKDGPLH IETTLSRKKY ESLCNDLLDR LFDPVNTVID DSGWNPEDID EVVLVGGSTR MPMVKQLVKT LVPNPPCQSV NPDEVVAIGA AIQGGILSGE LRDLLLNDVT PLSLGLETVG GLMKVLIPRN TSIPVRQSDV FSTSASNQSS VEIHIWQGER QMASDNKSLG KFKLSGIPPA PRGVPQVQVA FDIDANGLLE VSATDRTTGR KQSVSVTGGS NLNQNEVNKL IEESKVKASE DRKKRASIDQ KNNALTLVAQ AERRLRDASL ELGPYGAERQ QRSVEVAMRD VEDLLQDNDL QELEYAVGSL QEALFGLNRR LSAERKTDSN PIQGIKNTFG SLKDELFSDD YWDDDPWDYS QGRQNRNGDN NYGRRDLDPW DNDYYR //