ID NDHL_PROM1 Reviewed; 89 AA. AC A2C127; DT 04-NOV-2008, integrated into UniProtKB/Swiss-Prot. DT 20-FEB-2007, sequence version 1. DT 29-OCT-2014, entry version 47. DE RecName: Full=NAD(P)H-quinone oxidoreductase subunit L {ECO:0000255|HAMAP-Rule:MF_01355}; DE EC=1.6.5.- {ECO:0000255|HAMAP-Rule:MF_01355}; DE AltName: Full=NAD(P)H dehydrogenase I subunit L {ECO:0000255|HAMAP-Rule:MF_01355}; DE AltName: Full=NDH-1 subunit L; DE AltName: Full=NDH-L; GN Name=ndhL {ECO:0000255|HAMAP-Rule:MF_01355}; GN OrderedLocusNames=NATL1_06251; OS Prochlorococcus marinus (strain NATL1A). OC Bacteria; Cyanobacteria; Prochlorales; Prochlorococcaceae; OC Prochlorococcus. OX NCBI_TaxID=167555; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=NATL1A; RX PubMed=18159947; DOI=10.1371/journal.pgen.0030231; RA Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., RA Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., RA Steglich C., Church G.M., Richardson P., Chisholm S.W.; RT "Patterns and implications of gene gain and loss in the evolution of RT Prochlorococcus."; RL PLoS Genet. 3:2515-2528(2007). CC -!- FUNCTION: NDH-1 shuttles electrons from an unknown electron donor, CC via FMN and iron-sulfur (Fe-S) centers, to quinones in the CC respiratory and/or the photosynthetic chain. The immediate CC electron acceptor for the enzyme in this species is believed to be CC plastoquinone. Couples the redox reaction to proton translocation, CC and thus conserves the redox energy in a proton gradient. CC Cyanobacterial NDH-1 also plays a role in inorganic carbon- CC concentration. {ECO:0000255|HAMAP-Rule:MF_01355}. CC -!- CATALYTIC ACTIVITY: NAD(P)H + plastoquinone = NAD(P)(+) + CC plastoquinol. {ECO:0000255|HAMAP-Rule:MF_01355}. CC -!- SUBUNIT: NDH-1 can be composed of about 15 different subunits; CC different subcomplexes with different compositions have been CC identified which probably have different functions. CC {ECO:0000255|HAMAP-Rule:MF_01355}. CC -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane CC {ECO:0000255|HAMAP-Rule:MF_01355}; Multi-pass membrane protein CC {ECO:0000255|HAMAP-Rule:MF_01355}. CC -!- SIMILARITY: Belongs to the complex I NdhL subunit family. CC {ECO:0000255|HAMAP-Rule:MF_01355}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000553; ABM75187.1; -; Genomic_DNA. DR RefSeq; WP_011823352.1; NC_008819.1. DR RefSeq; YP_001014452.1; NC_008819.1. DR STRING; 167555.NATL1_06251; -. DR EnsemblBacteria; ABM75187; ABM75187; NATL1_06251. DR GeneID; 4779494; -. DR KEGG; pme:NATL1_06251; -. DR PATRIC; 23018813; VBIProMar31285_0637. DR eggNOG; NOG08765; -. DR HOGENOM; HOG000022604; -. DR KO; K05583; -. DR OMA; MNNRWNV; -. DR OrthoDB; EOG6Q2SSH; -. DR BioCyc; PMAR167555:GI3K-643-MONOMER; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0042651; C:thylakoid membrane; IEA:UniProtKB-HAMAP. DR GO; GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; IEA:UniProtKB-HAMAP. DR GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW. DR GO; GO:0006810; P:transport; IEA:UniProtKB-KW. DR HAMAP; MF_01355; NDH1_NDH1L; 1. DR InterPro; IPR019654; NADH-quinone_OxRdatse_su_L. DR Pfam; PF10716; NdhL; 1. PE 3: Inferred from homology; KW Complete proteome; Membrane; NAD; NADP; Oxidoreductase; Plastoquinone; KW Quinone; Thylakoid; Transmembrane; Transmembrane helix; Transport. FT CHAIN 1 89 NAD(P)H-quinone oxidoreductase subunit L. FT /FTId=PRO_0000353680. FT TRANSMEM 29 46 Helical. {ECO:0000255|HAMAP- FT Rule:MF_01355}. FT TRANSMEM 59 79 Helical. {ECO:0000255|HAMAP- FT Rule:MF_01355}. SQ SEQUENCE 89 AA; 10194 MW; 398F536FCEBE1AF4 CRC64; MSLISIVCLI PFGLIGAVNP IITLSAYAVL GGMYLFVVPL FLFYWMNNRW NVMGKFERLF IYGLVFLFFP GMVLFAPFLN LRMNGKEES //