ID   A2BRA1_PROMS            Unreviewed;       328 AA.
AC   A2BRA1;
DT   20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   20-FEB-2007, sequence version 1.
DT   02-OCT-2007, entry version 8.
DE   Putative Methionyl-tRNA formyltransferase (EC 2.1.2.9).
GN   Name=fmt; OrderedLocusNames=A9601_10281;
OS   Prochlorococcus marinus (strain AS9601).
OC   Bacteria; Cyanobacteria; Prochlorales; Prochlorococcaceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=146891;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Chisholm S., Huang K., Martiny A., Kettler G., Coleman M., Keller K.,
RA   Arkin A., Coe A., Rodrigue S., Ferriera S., Johnson J., Kravitz S.,
RA   Beeson K., Sutton G.G., Rogers Y.-H., Friedman R., Frazier M.,
RA   Venter J.C.;
RL   Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Modifies the free amino group of the aminoacyl moiety of
CC       methionyl-tRNA(fMet). The formyl group appears to play a dual role
CC       in the initiator identity of N-formylmethionyl-tRNA by: (I)
CC       promoting its recognition by IF2 and (II) impairing its binding to
CC       EFTu-GTP (By similarity).
CC   -!- CATALYTIC ACTIVITY: 10-formyltetrahydrofolate + L-methionyl-
CC       tRNA(fMet) + H(2)O = tetrahydrofolate + N-formylmethionyl-
CC       tRNA(fMet).
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DR   EMBL; CP000551; ABM70312.1; -; Genomic_DNA.
DR   RefSeq; YP_001009419.1; -.
DR   GeneID; 4717739; -.
DR   GO; GO:0004479; F:methionyl-tRNA formyltransferase activity; IEA:EC.
DR   InterPro; IPR005794; Fmt.
DR   InterPro; IPR005793; Formyl_trans_C.
DR   InterPro; IPR002376; Formyl_transf_N.
DR   InterPro; IPR015518; Met_tRNA_Form_TA-like.
DR   Gene3D; G3DSA:3.10.25.10; Formyl_trans_C; 1.
DR   Gene3D; G3DSA:3.40.50.170; Formyl_transf_N; 1.
DR   PANTHER; PTHR11138; Met_tRNA_Form_TA-like; 1.
DR   Pfam; PF02911; Formyl_trans_C; 1.
DR   Pfam; PF00551; Formyl_trans_N; 1.
DR   TIGRFAMs; TIGR00460; fmt; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Methyltransferase; Protein biosynthesis;
KW   Transferase.
SQ   SEQUENCE   328 AA;  37090 MW;  4AA5388674349BEB CRC64;
     MRIIFWGTPE YSIASLDIFI KSKHEVIGVV SQPDKKRSRG NKLISSPVKS FAEQESIKIY
     TPVKIRDNIH FINELKSLSC DLFIVIAYGK ILPKEILEIP KFGCWNAHAS LLPRWRGAAP
     IQWSLIKGDK FTGVGIMKMN EGLDTGDLLL EEKIKIGNED NLNTLSEKLS ILSAKLFLKA
     ASLLEENFYK NTKSQLTKQN SLGREITYAR MIEKSDFRVD WGNQAIAISQ KIKGLYPRAN
     TIFRGKNLKI LKIKVLSSDE IKNEKYLFMS DYSRPGIILA VIEDEGIIIS TKTDPIILLE
     AKLEGKNISS KKQLIQQLKP SVGEYLSD
//