ID A2AMQ5_MOUSE Unreviewed; 427 AA. AC A2AMQ5; DT 20-FEB-2007, integrated into UniProtKB/TrEMBL. DT 20-FEB-2007, sequence version 1. DT 18-SEP-2013, entry version 48. DE RecName: Full=Phosphatidate cytidylyltransferase; DE EC=2.7.7.41; GN Name=Cds2; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] RP IDENTIFICATION. RC STRAIN=C57BL/6J; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- CATALYTIC ACTIVITY: CTP + phosphatidate = diphosphate + CDP- CC diacylglycerol. CC -!- PATHWAY: Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CC CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3. CC -!- SIMILARITY: Belongs to the CDS family. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL807793; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR IPI; IPI00755231; -. DR PRIDE; A2AMQ5; -. DR Ensembl; ENSMUST00000089461; ENSMUSP00000086886; ENSMUSG00000058793. DR UCSC; uc029ueu.1; mouse. DR MGI; MGI:1332236; Cds2. DR GeneTree; ENSGT00390000016175; -. DR HOGENOM; HOG000209582; -. DR HOVERGEN; HBG002485; -. DR UniPathway; UPA00557; UER00614. DR NextBio; 35543703; -. DR ArrayExpress; A2AMQ5; -. DR GO; GO:0005783; C:endoplasmic reticulum; IDA:MGI. DR GO; GO:0016020; C:membrane; IEA:InterPro. DR GO; GO:0004605; F:phosphatidate cytidylyltransferase activity; IEA:InterPro. DR InterPro; IPR000374; PC_trans. DR InterPro; IPR016720; PC_Trfase_euk. DR Pfam; PF01148; CTP_transf_1; 1. DR PIRSF; PIRSF018269; PC_trans_euk; 1. DR PROSITE; PS01315; CDS; 1. PE 2: Evidence at transcript level; KW Complete proteome; Membrane; Nucleotidyltransferase; KW Reference proteome; Transferase; Transmembrane. SQ SEQUENCE 427 AA; 49294 MW; F67EF48633FAF3E0 CRC64; MESESEAKLD GETASDSESR AETAPLPTSV DDTPEVLNRA LSNLSSRWKN WWVRGILTLA MIAFFFIIIY LGPMVLMMIV MCVQIKCFHE IITIGYNVYH SYDLPWFRTL SWYFLLCVNY FFYGETVTDY FFTLVQREEP LRILSKYHRF ISFALYLTGF CMFVLSLVKK HYRLQFYMFG WTHVTLLIVV TQSHLVIHNL FEGMIWFIVP ISCVICNDIM AYMFGFFFGR TPLIKLSPKK TWEGFIGGFF ATVVFGLLLS YVMSGYRCFV CPVEYNNDTN SFTVDCEPSD LFRLQEYNIP GVIQSAIGWK TVRMYPFQIH SIALSTFASL IGPFGGFFAS GFKRAFKIKD FANTIPGHGG IMDRFDCQYL MATFVNVYIA SFIRGPNPSK LIQQFLTLRP DQQLHIFNTL KSHLTDKGIL TSALEDE //