ID A2AAX8_MOUSE Unreviewed; 182 AA. AC A2AAX8; DT 05-FEB-2008, integrated into UniProtKB/TrEMBL. DT 05-FEB-2008, sequence version 1. DT 12-AUG-2020, entry version 71. DE SubName: Full=GATOR complex protein NPRL3 {ECO:0000313|Ensembl:ENSMUSP00000123219}; DE Flags: Fragment; GN Name=Nprl3 {ECO:0000313|Ensembl:ENSMUSP00000123219, GN ECO:0000313|MGI:MGI:109258}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000123219, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000123219, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000123219, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000213|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and expression."; RL Cell 143:1174-1189(2010). RN [3] {ECO:0000313|Ensembl:ENSMUSP00000123219} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000123219}; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- SIMILARITY: Belongs to the NPR3 family. CC {ECO:0000256|ARBA:ARBA00010546}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL662780; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL929446; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; BX248420; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR MaxQB; A2AAX8; -. DR PRIDE; A2AAX8; -. DR Antibodypedia; 1565; 79 antibodies. DR Ensembl; ENSMUST00000129010; ENSMUSP00000123219; ENSMUSG00000020289. DR MGI; MGI:109258; Nprl3. DR GeneTree; ENSGT00390000015916; -. DR HOGENOM; CLU_1485329_0_0_1; -. DR ChiTaRS; Nprl3; mouse. DR Proteomes; UP000000589; Chromosome 11. DR Bgee; ENSMUSG00000020289; Expressed in bone marrow and 188 other tissues. DR ExpressionAtlas; A2AAX8; baseline and differential. DR GO; GO:0034198; P:cellular response to amino acid starvation; IEA:InterPro. DR GO; GO:0032007; P:negative regulation of TOR signaling; IEA:InterPro. DR InterPro; IPR005365; Npr3. DR PANTHER; PTHR13153; PTHR13153; 1. DR Pfam; PF03666; NPR3; 1. PE 1: Evidence at protein level; KW Proteomics identification {ECO:0000213|EPD:A2AAX8, KW ECO:0000213|MaxQB:A2AAX8}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT REGION 27..69 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 31..47 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 50..64 FT /note="Polyampholyte" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 182 FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000123219" SQ SEQUENCE 182 AA; 20213 MW; 9E7574532DB07F6E CRC64; MGDNTSPISV ILVSSGSRGN KLLFRYPFQR SQEHPASQTN KPRSRYAVNN TGEHADDQDG DSSKPCPPTD EQLVAGFSDV ILATILATKS EMCGQKFELK IDNVRFVGHP TLLQHALGQV SKTDPSPKRE APTMILFNVV FALRANADPS VINCLHNLSR RIATVLQHEE RRCQYLTREA KL //