ID A2AAX8_MOUSE Unreviewed; 182 AA. AC A2AAX8; DT 05-FEB-2008, integrated into UniProtKB/TrEMBL. DT 05-FEB-2008, sequence version 1. DT 16-OCT-2019, entry version 66. DE SubName: Full=GATOR complex protein NPRL3 {ECO:0000313|Ensembl:ENSMUSP00000123219}; DE Flags: Fragment; GN Name=Nprl3 {ECO:0000313|Ensembl:ENSMUSP00000123219, GN ECO:0000313|MGI:MGI:109258}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000123219, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000123219, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000123219, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000213|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and RT expression."; RL Cell 143:1174-1189(2010). RN [3] {ECO:0000313|Ensembl:ENSMUSP00000123219} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000123219}; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL662780; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL929446; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; BX248420; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR MaxQB; A2AAX8; -. DR PRIDE; A2AAX8; -. DR Ensembl; ENSMUST00000129010; ENSMUSP00000123219; ENSMUSG00000020289. DR MGI; MGI:109258; Nprl3. DR GeneTree; ENSGT00390000015916; -. DR ChiTaRS; Nprl3; mouse. DR Proteomes; UP000000589; Chromosome 11. DR Bgee; ENSMUSG00000020289; Expressed in 165 organ(s), highest expression level in bone marrow. DR ExpressionAtlas; A2AAX8; baseline and differential. DR GO; GO:0034198; P:cellular response to amino acid starvation; IEA:InterPro. DR GO; GO:0032007; P:negative regulation of TOR signaling; IEA:InterPro. DR InterPro; IPR005365; Npr3. DR PANTHER; PTHR13153; PTHR13153; 1. DR Pfam; PF03666; NPR3; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Proteomics identification {ECO:0000213|EPD:A2AAX8, KW ECO:0000213|MaxQB:A2AAX8}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT REGION 27 69 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 31 47 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 50 64 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT NON_TER 182 182 {ECO:0000313|Ensembl:ENSMUSP00000123219}. SQ SEQUENCE 182 AA; 20213 MW; 9E7574532DB07F6E CRC64; MGDNTSPISV ILVSSGSRGN KLLFRYPFQR SQEHPASQTN KPRSRYAVNN TGEHADDQDG DSSKPCPPTD EQLVAGFSDV ILATILATKS EMCGQKFELK IDNVRFVGHP TLLQHALGQV SKTDPSPKRE APTMILFNVV FALRANADPS VINCLHNLSR RIATVLQHEE RRCQYLTREA KL //