ID A1Z2M2_HUMAN Unreviewed; 82 AA. AC A1Z2M2; DT 06-FEB-2007, integrated into UniProtKB/TrEMBL. DT 06-FEB-2007, sequence version 1. DT 26-NOV-2014, entry version 40. DE SubName: Full=Interferon gamma {ECO:0000313|EMBL:ABM53145.1}; DE Flags: Fragment; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:ABM53145.1}; RN [1] {ECO:0000313|EMBL:ABM53145.1} RP NUCLEOTIDE SEQUENCE. RA Jeong A.-R., Nakamura S., Mitsunaga F.; RT "Comparison of Gene Expression Profile of Cytokines and Their RT Receptors in Human and Nonhuman Primates."; RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EF173872; ABM53145.1; -; mRNA. DR UniGene; Hs.856; -. DR PRIDE; A1Z2M2; -. DR NextBio; 35460650; -. DR Bgee; A1Z2M2; -. DR ExpressionAtlas; A1Z2M2; baseline and differential. DR GO; GO:0009897; C:external side of plasma membrane; IEA:Ensembl. DR GO; GO:0005615; C:extracellular space; IEA:Ensembl. DR GO; GO:0002250; P:adaptive immune response; IEA:Ensembl. DR GO; GO:0019882; P:antigen processing and presentation; IEA:Ensembl. DR GO; GO:0002302; P:CD8-positive, alpha-beta T cell differentiation involved in immune response; IEA:Ensembl. DR GO; GO:0071351; P:cellular response to interleukin-18; IEA:Ensembl. DR GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl. DR GO; GO:0042742; P:defense response to bacterium; IEA:Ensembl. DR GO; GO:0042832; P:defense response to protozoan; IEA:Ensembl. DR GO; GO:0051607; P:defense response to virus; IEA:Ensembl. DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:Ensembl. DR GO; GO:0006959; P:humoral immune response; IEA:Ensembl. DR GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl. DR GO; GO:0044130; P:negative regulation of growth of symbiont in host; IEA:Ensembl. DR GO; GO:0003340; P:negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis; IEA:Ensembl. DR GO; GO:0072308; P:negative regulation of metanephric nephron tubule epithelial cell differentiation; IEA:Ensembl. DR GO; GO:0031642; P:negative regulation of myelination; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR GO; GO:0001781; P:neutrophil apoptotic process; IEA:Ensembl. DR GO; GO:0030593; P:neutrophil chemotaxis; IEA:Ensembl. DR GO; GO:0045785; P:positive regulation of cell adhesion; IEA:Ensembl. DR GO; GO:0045080; P:positive regulation of chemokine biosynthetic process; IEA:Ensembl. DR GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; IEA:Ensembl. DR GO; GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IEA:Ensembl. DR GO; GO:0032735; P:positive regulation of interleukin-12 production; IEA:Ensembl. DR GO; GO:0045410; P:positive regulation of interleukin-6 biosynthetic process; IEA:Ensembl. DR GO; GO:0048304; P:positive regulation of isotype switching to IgG isotypes; IEA:Ensembl. DR GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl. DR GO; GO:0045348; P:positive regulation of MHC class II biosynthetic process; IEA:Ensembl. DR GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl. DR GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IEA:Ensembl. DR GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IEA:Ensembl. DR GO; GO:0032224; P:positive regulation of synaptic transmission, cholinergic; IEA:Ensembl. DR GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl. DR GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl. DR GO; GO:0042511; P:positive regulation of tyrosine phosphorylation of Stat1 protein; IEA:Ensembl. DR GO; GO:2000345; P:regulation of hepatocyte proliferation; IEA:Ensembl. DR GO; GO:0098908; P:regulation of neuronal action potential; IEA:Ensembl. DR GO; GO:0002026; P:regulation of the force of heart contraction; IEA:Ensembl. DR GO; GO:0042493; P:response to drug; IEA:Ensembl. DR GO; GO:0050954; P:sensory perception of mechanical stimulus; IEA:Ensembl. DR Gene3D; 1.20.1250.10; -; 1. DR InterPro; IPR009079; 4_helix_cytokine-like_core. DR InterPro; IPR012351; 4_helix_cytokine_core. DR InterPro; IPR002069; Interferon_gamma. DR PANTHER; PTHR11419; PTHR11419; 1. DR Pfam; PF00714; IFN-gamma; 1. DR ProDom; PD002435; Interferon_gamma; 1. DR SUPFAM; SSF47266; SSF47266; 1. PE 2: Evidence at transcript level; FT NON_TER 1 1 {ECO:0000313|EMBL:ABM53145.1}. FT NON_TER 82 82 {ECO:0000313|EMBL:ABM53145.1}. SQ SEQUENCE 82 AA; 9668 MW; E5485D612BF7EF60 CRC64; FKLFKNFKDD QSIQKSVETI KEDMNVKFFN SNKKKRDDFE KLTNYSVTDL NVQRKAIHEL IQVMAELSPA AKTGKRKRSQ ML //