ID GREA_CHLPD Reviewed; 159 AA. AC A1BHJ3; DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot. DT 23-JAN-2007, sequence version 1. DT 16-NOV-2011, entry version 41. DE RecName: Full=Transcription elongation factor greA; DE AltName: Full=Transcript cleavage factor greA; GN Name=greA; OrderedLocusNames=Cpha266_1854; OS Chlorobium phaeobacteroides (strain DSM 266). OC Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae; OC Chlorobium/Pelodictyon group; Chlorobium. OX NCBI_TaxID=290317; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DSM 266; RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., RA Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E., RA Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T., RA Overmann J., Bryant D.A., Richardson P.; RT "Complete sequence of Chlorobium phaeobacteroides DSM 266."; RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Necessary for efficient RNA polymerase transcription CC elongation past template-encoded arresting sites. The arresting CC sites in DNA have the property of trapping a certain fraction of CC elongating RNA polymerases that pass through, resulting in locked CC ternary complexes. Cleavage of the nascent transcript by cleavage CC factors such as greA or greB allows the resumption of elongation CC from the new 3'terminus. GreA releases sequences of 2 to 3 CC nucleotides (By similarity). CC -!- SIMILARITY: Belongs to the greA/greB family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000492; ABL65870.1; -; Genomic_DNA. DR RefSeq; YP_912294.1; NC_008639.1. DR ProteinModelPortal; A1BHJ3; -. DR STRING; A1BHJ3; -. DR GeneID; 4571196; -. DR GenomeReviews; CP000492_GR; Cpha266_1854. DR KEGG; cph:Cpha266_1854; -. DR NMPDR; fig|290317.7.peg.1951; -. DR eggNOG; COG0782; -. DR HOGENOM; HBG753387; -. DR OMA; HEARKEQ; -. DR ProtClustDB; PRK00226; -. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro. DR GO; GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. DR HAMAP; MF_00105; GreA_GreB; 1; -. DR InterPro; IPR018151; TF_GreA/GreB_CS. DR InterPro; IPR006359; Tscrpt_elong_fac_GreA. DR InterPro; IPR023459; Tscrpt_elong_fac_GreA/B. DR InterPro; IPR001437; Tscrpt_elong_fac_GreA/B_C. DR InterPro; IPR022691; Tscrpt_elong_fac_GreA/B_N. DR Gene3D; G3DSA:1.10.287.180; GreA_GreB_reg; 1. DR Gene3D; G3DSA:3.10.50.30; GreA_GreB_reg; 1. DR KO; K03624; -. DR Pfam; PF01272; GreA_GreB; 1. DR Pfam; PF03449; GreA_GreB_N; 1. DR PIRSF; PIRSF006092; GreA_GreB; 1. DR SUPFAM; SSF46557; GreA_GreB; 1. DR TIGRFAMs; TIGR01462; GreA; 1. DR PROSITE; PS00829; GREAB_1; 1. DR PROSITE; PS00830; GREAB_2; 1. PE 3: Inferred from homology; KW Coiled coil; Complete proteome; DNA-binding; Transcription; KW Transcription regulation. FT CHAIN 1 159 Transcription elongation factor greA. FT /FTId=PRO_1000034254. FT COILED 47 73 Potential. SQ SEQUENCE 159 AA; 18084 MW; 48DFA0F4A200C960 CRC64; MNDRIYLTRD GYNRLKEELY VLVHQKRKEV LEKIAEARAH GDLSENAEYD AAREEQSLTE AHIADLENKL STATILDPKQ VKTDKVYILT SVKLRDLDKE GEIIEYTLVS SEEADTDLGK ISVRSPVGRA LIGKTVGEKV QIMVPKGELH YEILEIFVK //