ID A1A703_DROME Unreviewed; 614 AA. AC A1A703; DT 23-JAN-2007, integrated into UniProtKB/TrEMBL. DT 23-JAN-2007, sequence version 1. DT 10-AUG-2010, entry version 28. DE SubName: Full=IP17340p; DE SubName: Full=IP17540p; DE SubName: Full=SNF4/AMP-activated protein kinase gamma subunit, isoform M; DE EC=2.7.11.-; DE SubName: Full=SNF4/AMP-activated protein kinase gamma subunit, isoform N; DE EC=2.7.11.-; GN Name=SNF4Agamma; ORFNames=Dmel_CG17299; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX MEDLINE=20196006; PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., RA Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., RA Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., RA Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX MEDLINE=22426069; PubMed=12537572; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BT029676; ABL75733.1; -; mRNA. DR EMBL; BT029715; ABL75772.1; -; mRNA. DR EMBL; AE014297; ABW08716.1; -; Genomic_DNA. DR EMBL; AE014297; ABW08717.1; -; Genomic_DNA. DR RefSeq; NP_001036736.2; -. DR RefSeq; NP_001097854.1; -. DR RefSeq; NP_001097855.1; -. DR UniGene; Dm.16656; -. DR ProteinModelPortal; A1A703; -. DR SMR; A1A703; 134-432. DR STRING; A1A703; -. DR PRIDE; A1A703; -. DR EnsemblMetazoa; FBtr0084018; FBpp0083421; FBgn0025803. DR EnsemblMetazoa; FBtr0084019; FBpp0083422; FBgn0025803. DR EnsemblMetazoa; FBtr0084020; FBpp0083423; FBgn0025803. DR EnsemblMetazoa; FBtr0084021; FBpp0083424; FBgn0025803. DR EnsemblMetazoa; FBtr0084022; FBpp0083425; FBgn0025803. DR EnsemblMetazoa; FBtr0084024; FBpp0083427; FBgn0025803. DR EnsemblMetazoa; FBtr0110937; FBpp0110237; FBgn0025803. DR EnsemblMetazoa; FBtr0110938; FBpp0110238; FBgn0025803. DR EnsemblMetazoa; FBtr0110939; FBpp0110239; FBgn0025803. DR EnsemblMetazoa; FBtr0112915; FBpp0111828; FBgn0025803. DR EnsemblMetazoa; FBtr0112916; FBpp0111829; FBgn0025803. DR EnsemblMetazoa; FBtr0301585; FBpp0290800; FBgn0025803. DR EnsemblMetazoa; FBtr0301586; FBpp0290801; FBgn0025803. DR EnsemblMetazoa; FBtr0301587; FBpp0290802; FBgn0025803. DR EnsemblMetazoa; FBtr0301588; FBpp0290803; FBgn0025803. DR EnsemblMetazoa; FBtr0301589; FBpp0290804; FBgn0025803. DR GeneID; 42515; -. DR KEGG; dme:Dmel_CG17299; -. DR UCSC; CG17299-RM; d. melanogaster. DR CTD; 42515; -. DR FlyBase; FBgn0025803; SNF4Agamma. DR NextBio; 829192; -. DR Bgee; A1A703; -. DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW. DR GO; GO:0042632; P:cholesterol homeostasis; IMP:FlyBase. DR GO; GO:0045787; P:positive regulation of cell cycle; IGI:FlyBase. DR InterPro; IPR000644; Cysta_beta_synth_core. DR Pfam; PF00571; CBS; 3. DR SMART; SM00116; CBS; 4. DR PROSITE; PS51371; CBS; 4. PE 2: Evidence at transcript level; KW Complete proteome; Kinase; Transferase. SQ SEQUENCE 614 AA; 67801 MW; 3C4AE04CE010B062 CRC64; MSAVKRWIYR HTHSSSSATP TSPGPPPVSP TNKTRRGRSH SLDVQSLPGI RAMMVNSRAA AHQQQLAVQS AHMRRASADL EKRRASVGAA GRGLRGDGTL DPHHAAILFR DSRGLPVADP FLEKVNLSDL EEDDSQIFVK FFRFHKCYDL IPTSAKLVVF DTQLLVKKAF YALVYNGVRA APLWDSEKQQ FVGMLTITDF IKILQMYYKS PNASMEQLEE HKLDTWRSVL HNQVMPLVSI GPDASLYDAI KILIHSRIHR LPVIDPATGN VLYILTHKRI LRFLFLYINE LPKPAYMQKS LRELKIGTYN NIETADETTS IITALKKFVE RRVSALPLVD SDGRLVDIYA KFDVINLAAE KTYNDLDVSL RKANEHRNEW FEGVQKCNLD ESLYTIMERI VRAEVHRLVV VDENRKVIGI ISLSDILLYL VLRPSGEGVG GSESSLRASD PVLLRKVAEV EIPATAAAAT TTTPPRSPSA GSGNRSLIED IPEEETAPAR SDDADSDNNK SASEDKANNN QHDQTTTAAT ANGDSNNSPV EVSFADEAQE EEAADQVERS NCDDDDQPAL AEIERKNASM DDDEDDGMSS AVSAASALGQ SLTPAAQEMA LVSE //