ID A0T1V1_9SAUR Unreviewed; 343 AA. AC A0T1V1; DT 09-JAN-2007, integrated into UniProtKB/TrEMBL. DT 09-JAN-2007, sequence version 1. DT 10-JUN-2008, entry version 10. DE NADH-ubiquinone oxidoreductase chain 2 (EC 1.6.5.3). GN Name=ND2; OS Orthriophis taeniurus. OG Mitochondrion. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Lepidosauria; Squamata; Scleroglossa; Serpentes; Colubroidea; OC Colubridae; Colubrinae; Orthriophis. OX NCBI_TaxID=74398; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=17113316; DOI=10.1016/j.ympev.2006.09.009; RA Burbrink F.T., Lawson R.; RT "How and when did Old World ratsnakes disperse into the New World?"; RL Mol. Phylogenet. Evol. 43:173-189(2007). CC -!- FUNCTION: Core subunit of the mitochondrial membrane respiratory CC chain NADH dehydrogenase (Complex I) that is believed to belong to CC the minimal assembly required for catalysis. Complex I functions CC in the transfer of electrons from NADH to the respiratory chain. CC The immediate electron acceptor for the enzyme is believed to be CC ubiquinone (By similarity). CC -!- CATALYTIC ACTIVITY: NADH + ubiquinone = NAD(+) + ubiquinol. CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass CC membrane protein (By similarity). CC -!- SIMILARITY: Belongs to the complex I subunit 2 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EF076707; ABK63247.1; -; Genomic_DNA. DR HOVERGEN; A0T1V1; -. DR GO; GO:0005746; C:mitochondrial respiratory chain; IEA:UniProtKB-KW. DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro. DR GO; GO:0006120; P:mitochondrial electron transport, NADH to u...; IEA:InterPro. DR GO; GO:0006810; P:transport; IEA:UniProtKB-KW. DR InterPro; IPR010933; NADH_DHase_su2_C. DR InterPro; IPR003917; NADHub_OxRdtase_2. DR InterPro; IPR001750; Oxidored_q1. DR Pfam; PF06444; NADH_dehy_S2_C; 1. DR Pfam; PF00361; Oxidored_q1; 1. DR PRINTS; PR01436; NADHDHGNASE2. PE 3: Inferred from homology; KW Electron transport; Membrane; Mitochondrion; NAD; Oxidoreductase; KW Respiratory chain; Transport; Ubiquinone. SQ SEQUENCE 343 AA; 38232 MW; ACF358B942ACF1AB CRC64; MNLTSWSIIT TSIILSTTMI TSTTHWLMTW VCLEINTLSM IPLISKPNHP RATEAATKYY LTQTMASTTI LFAATTNALS TSNWDMHLMT EPVATTITTM ALMMKMAAAP FHFWLPDVSQ GTTTLTALTI LTWQKIAPLT IMLTTHNKTN ITLMLLSAVL SITAGGLGSL NQTQLRKLMA FSSIAHTGWI MATMTMAPNI SMLTFMIYIT ATTPMFLLMN TTNSMTIKDI GTMWTNSPHI MMISLTTILS LGGLPPLSGF MPKWLILNNM TTMNMIVEAT LMTMTSLLSL YVYMRLMYMS SMTLPPHTTL TSLKWRTQNK KHRMTTSTMA MITMLMLPLS PNM //