ID A0AAJ7RC35_CEPCN Unreviewed; 576 AA. AC A0AAJ7RC35; DT 24-JUL-2024, integrated into UniProtKB/TrEMBL. DT 24-JUL-2024, sequence version 1. DT 27-NOV-2024, entry version 3. DE SubName: Full=Protein singed isoform X1 {ECO:0000313|RefSeq:XP_024937802.1}; GN Name=LOC107264818 {ECO:0000313|RefSeq:XP_024937802.1}; OS Cephus cinctus (Wheat stem sawfly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Hymenoptera; Cephoidea; Cephidae; Cephus. OX NCBI_TaxID=211228 {ECO:0000313|Proteomes:UP000694920, ECO:0000313|RefSeq:XP_024937802.1}; RN [1] {ECO:0000313|RefSeq:XP_024937802.1} RP IDENTIFICATION. RG RefSeq; RL Submitted (AUG-2024) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton CC {ECO:0000256|ARBA:ARBA00004245}. CC -!- SIMILARITY: Belongs to the fascin family. CC {ECO:0000256|ARBA:ARBA00007415}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; XP_024937802.1; XM_025082034.1. DR Proteomes; UP000694920; Unplaced. DR GO; GO:0015629; C:actin cytoskeleton; IEA:TreeGrafter. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW. DR GO; GO:0051015; F:actin filament binding; IEA:InterPro. DR GO; GO:0030674; F:protein-macromolecule adaptor activity; IEA:InterPro. DR GO; GO:0051017; P:actin filament bundle assembly; IEA:TreeGrafter. DR GO; GO:0016477; P:cell migration; IEA:TreeGrafter. DR GO; GO:0007163; P:establishment or maintenance of cell polarity; IEA:TreeGrafter. DR CDD; cd00257; Fascin; 4. DR FunFam; 2.80.10.50:FF:000008; Fascin; 1. DR FunFam; 2.80.10.50:FF:000010; Fascin; 1. DR FunFam; 2.80.10.50:FF:000015; Fascin; 1. DR FunFam; 2.80.10.50:FF:000064; Fascin; 1. DR Gene3D; 2.80.10.50; -; 4. DR InterPro; IPR008999; Actin-crosslinking. DR InterPro; IPR010431; Fascin. DR InterPro; IPR022768; Fascin-domain. DR PANTHER; PTHR10551; FASCIN; 1. DR PANTHER; PTHR10551:SF9; PROTEIN SINGED; 1. DR Pfam; PF06268; Fascin; 4. DR SUPFAM; SSF50405; Actin-crosslinking proteins; 4. PE 3: Inferred from homology; KW Actin-binding {ECO:0000256|ARBA:ARBA00023203}; KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490}; KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212}; KW Reference proteome {ECO:0000313|Proteomes:UP000694920}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1..19 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 20..576 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5042610086" FT DOMAIN 81..190 FT /note="Fascin" FT /evidence="ECO:0000259|Pfam:PF06268" FT DOMAIN 200..329 FT /note="Fascin" FT /evidence="ECO:0000259|Pfam:PF06268" FT DOMAIN 343..447 FT /note="Fascin" FT /evidence="ECO:0000259|Pfam:PF06268" FT DOMAIN 485..575 FT /note="Fascin" FT /evidence="ECO:0000259|Pfam:PF06268" SQ SEQUENCE 576 AA; 64223 MW; FEA94707BB26A296 CRC64; MLRLLSCMLF AFISTEIHSQ WRNKWEDKTS KRTSPFFGHF CNADFHRGIV TMQNNGSESG SSENGVDRTG WTVGLINGKF KYLTAETFGF KINANGASLK KKQLWTLEGS EHQVFLRSHL DRYLAVDQFG NVTCEAEDPS DPGCAFQIQL ASDGSGRWAL KNVQRGYFLG SSQDELKCTA KAPGEAEYWL VHLAARPQVN LRSAGRKRFA HLSAAQDEIH VDAPVPWGED TLFTLEFRPA ATADNDNSAG NRAKSEGGHY ALHTCNNKYL ARDGKLLESC TRDCLYAAEF HAGLLALRDV HGAYLAPIGS KAVLKSRSTT VTRDELFSLE ESLPQASFVA ALNQRYVSVK QGVDVTANQD EISGHETFQL EFDRVTKRWY IRTMQDRYWS LEAGGGIQAS EHKRSSNALF DLVWQPEDGT VALRANNGKF LATKRSGHLY ANADSPSSGD SDVSKYYFYL MNRPVLVLRC EQGFVGPKSA VSPKLECNKA GYETIRVERC ERGVVRFKGQ NGKYWHADSE GVTVDADAAS DGFYLELREP SRICIKCTDG RYLTAGKNGA LRLGETDYET ATKWEF //