ID A0AAE6Y635_STRAT Unreviewed; 270 AA. AC A0AAE6Y635; DT 29-MAY-2024, integrated into UniProtKB/TrEMBL. DT 29-MAY-2024, sequence version 1. DT 02-OCT-2024, entry version 3. DE SubName: Full=SGNH/GDSL hydrolase family protein {ECO:0000313|EMBL:QIT43660.1}; GN ORFNames=HCX60_09090 {ECO:0000313|EMBL:QIT43660.1}; OS Streptomyces antibioticus. OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales; OC Streptomycetaceae; Streptomyces. OX NCBI_TaxID=1890 {ECO:0000313|EMBL:QIT43660.1, ECO:0000313|Proteomes:UP000502504}; RN [1] {ECO:0000313|EMBL:QIT43660.1, ECO:0000313|Proteomes:UP000502504} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DSM 41481 {ECO:0000313|EMBL:QIT43660.1, RC ECO:0000313|Proteomes:UP000502504}; RA David M., Lejeune C., Abreu S., Thibessard A., Leblond P., Chaminade P., RA Virolle M.-J.; RT "Is there a link between lipid content and antibiotic production in RT Streptomyces?"; RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP050692; QIT43660.1; -; Genomic_DNA. DR Proteomes; UP000502504; Chromosome. DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro. DR CDD; cd01823; SEST_like; 1. DR Gene3D; 3.40.50.1110; SGNH hydrolase; 1. DR InterPro; IPR037460; SEST-like. DR InterPro; IPR013830; SGNH_hydro. DR InterPro; IPR036514; SGNH_hydro_sf. DR PANTHER; PTHR37981; LIPASE 2; 1. DR PANTHER; PTHR37981:SF1; SGNH_HYDRO DOMAIN-CONTAINING PROTEIN; 1. DR Pfam; PF13472; Lipase_GDSL_2; 1. DR SUPFAM; SSF52266; SGNH hydrolase; 1. PE 4: Predicted; KW Disulfide bond {ECO:0000256|PIRSR:PIRSR637460-2}; KW Hydrolase {ECO:0000313|EMBL:QIT43660.1}; Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1..26 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 27..270 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5042273193" FT DOMAIN 42..258 FT /note="SGNH hydrolase-type esterase" FT /evidence="ECO:0000259|Pfam:PF13472" FT ACT_SITE 46 FT /note="Nucleophile" FT /evidence="ECO:0000256|PIRSR:PIRSR637460-1" FT ACT_SITE 252 FT /evidence="ECO:0000256|PIRSR:PIRSR637460-1" FT DISULFID 63..88 FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2" FT DISULFID 129..137 FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2" FT DISULFID 187..233 FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2" SQ SEQUENCE 270 AA; 27619 MW; 1FFF713064C405E1 CRC64; MRRSRLVVFV SSLLLAAGAA LTGASAAQAS ASPLAAAGGY VALGDSYSSG VGAGSYISSS SSCKRSTKAY PYLWNAAHTP TSFTFAACSG AKTGDVLANQ LGGLSSTTGL VSITVGGNDA GFTDVMTTCV TSSDSTCVSR INTAKAYVDS TLPGKLDTVY STIRSKAPNA RVVVIGYPRF YKLGTVCVGL SETKRSAINN AADHLDTALA KRAAAHGFAF GDVRTTFAGH EICSGSSWLH SLNWLSIGDS YHPTASGQSG GYLPALERNA //