ID A0AA51BRS5_9CAUD Unreviewed; 435 AA. AC A0AA51BRS5; DT 24-JAN-2024, integrated into UniProtKB/TrEMBL. DT 24-JAN-2024, sequence version 1. DT 24-JUL-2024, entry version 4. DE RecName: Full=Integrase {ECO:0000256|ARBA:ARBA00016082}; GN Name=36 {ECO:0000313|EMBL:WMI34630.1}; GN ORFNames=SEA_CALM_36 {ECO:0000313|EMBL:WMI34630.1}; OS Mycobacterium phage Calm. OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; OC Vilmaviridae; Lclasvirinae; Bronvirus. OX NCBI_TaxID=3070631 {ECO:0000313|EMBL:WMI34630.1}; RN [1] {ECO:0000313|EMBL:WMI34630.1} RP NUCLEOTIDE SEQUENCE. RA Annobil L.M., AsieduAgyei K., Atrous Y.M., Bennett K.M., Bradley M.B., RA Brickner C., Brown M.J., Chenoweth P.C., Dail W.C., Dickens T.M., RA Wenhao F., Gebreselassie S., Goad L.M., Hille H.M., Huang Y., Hunter N.D., RA Jackson Q.D., Jafarzadeh K., Kim I., Kramer P.E., Kubovcik D.P., Le V.D., RA Leake A.C., Lovejoy J.S., Maloney J., Miller E.J., Mills T.Z., Miln D.K., RA Mincheff C.M., Mondy C.S., Obey U.B., Pommett E.J., Prochaska M., RA Purvis S., Rainer B.A., Ravva S., Roach A.T., Rosser A.J., Smith A.M., RA Smith C., Spruill B.S., Szymanowski E.G., Taylor K.L., Voshell S.M., RA White J.W., Williamson M., Wu Z., Zhao Z., Garlena R.A., Russell D.A., RA Pope W.H., Jacobs-Sera D., Hatfull G.F.; RL Submitted (MAY-2023) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the 'phage' integrase family. CC {ECO:0000256|ARBA:ARBA00008857}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; OQ995440; WMI34630.1; -; Genomic_DNA. DR Proteomes; UP001182481; Segment. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW. DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW. DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW. DR GO; GO:0046718; P:symbiont entry into host cell; IEA:UniProtKB-KW. DR CDD; cd01189; INT_ICEBs1_C_like; 1. DR Gene3D; 1.10.150.130; -; 1. DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1. DR InterPro; IPR044068; CB. DR InterPro; IPR011010; DNA_brk_join_enz. DR InterPro; IPR013762; Integrase-like_cat_sf. DR InterPro; IPR002104; Integrase_catalytic. DR InterPro; IPR010998; Integrase_recombinase_N. DR InterPro; IPR004107; Integrase_SAM-like_N. DR InterPro; IPR050808; Phage_Integrase. DR PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1. DR PANTHER; PTHR30629:SF6; PROPHAGE INTEGRASE INTA-RELATED; 1. DR Pfam; PF14659; Phage_int_SAM_3; 1. DR Pfam; PF00589; Phage_integrase; 1. DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1. DR PROSITE; PS51900; CB; 1. DR PROSITE; PS51898; TYR_RECOMBINASE; 1. PE 3: Inferred from homology; KW DNA integration {ECO:0000256|ARBA:ARBA00022908}; KW DNA recombination {ECO:0000256|ARBA:ARBA00023172}; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE- KW ProRule:PRU01248}; Hydrolase {ECO:0000256|ARBA:ARBA00022801}; KW Transferase {ECO:0000256|ARBA:ARBA00022679}; KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}. FT DOMAIN 77..163 FT /note="Core-binding (CB)" FT /evidence="ECO:0000259|PROSITE:PS51900" FT DOMAIN 185..425 FT /note="Tyr recombinase" FT /evidence="ECO:0000259|PROSITE:PS51898" SQ SEQUENCE 435 AA; 48892 MW; 3B303EBB308D019D CRC64; MAETDSKIKR RLRGDGGLTY DKSRGLYIGI VWVVGPDGKR RQKRVSSRKE SEALRKLNKL RADVLAGKIA TTLGKVKTVG EWLDYWLTVK KSECRPSTYE SYEGSARLYL KPHLGHIRLD KLTTPQVRDM LTKVRDGGGN TKASTRNPQK AYQALNNAMK LAVDEGVLDR NPVAPIKKPG HVKQQRGAFE TSAAVHLLKT AAALDDEDNP KRPKLASHWA AAFMTGARQA ELLGLEWDRV DFDRGVLDIS WQLQRLKYAH GCGLNSDGEP KCGRQRVGYC PERKFVPPPG FEYRHCHRSL FWTRPKSLAG ERTVPMAPLL LESLKVHKRL DKDPNPHNLV WHHRDGRPIS QEDDNEHWNR LVAAAGIEKR PREVVLHEAR NTAATMLLES GIDAKVIQTI LGHASILQTR DYQRVSLELS KSAVSNAFDA LLPSV //