ID A0AA37QPH0_9BRAD Unreviewed; 380 AA. AC A0AA37QPH0; DT 24-JAN-2024, integrated into UniProtKB/TrEMBL. DT 24-JAN-2024, sequence version 1. DT 02-OCT-2024, entry version 5. DE RecName: Full=ornithine decarboxylase {ECO:0000256|ARBA:ARBA00034138}; DE EC=4.1.1.17 {ECO:0000256|ARBA:ARBA00034138}; GN Name=speF {ECO:0000313|EMBL:GLH87545.1}; GN ORFNames=SSBR45R_50050 {ECO:0000313|EMBL:GLH87545.1}; OS Bradyrhizobium sp. SSBR45R. OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales; OC Nitrobacteraceae; Bradyrhizobium. OX NCBI_TaxID=2996007 {ECO:0000313|EMBL:GLH87545.1, ECO:0000313|Proteomes:UP001161291}; RN [1] {ECO:0000313|EMBL:GLH87545.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=SSBR45R {ECO:0000313|EMBL:GLH87545.1}; RA Hata S., Kojima S., Tsuda R., Kawajiri N., Kouchi H., Suzuki T., Uesaka K., RA Tanaka A.; RT "Draft genome sequence of photosynthetic Bradyrhizobium sp. strain SSB45R, RT from root nodules of Aeschynomene indica."; RL Submitted (NOV-2022) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=H(+) + L-ornithine = CO2 + putrescine; Xref=Rhea:RHEA:22964, CC ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:46911, CC ChEBI:CHEBI:326268; EC=4.1.1.17; CC Evidence={ECO:0000256|ARBA:ARBA00034037}; CC -!- COFACTOR: CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; CC Evidence={ECO:0000256|ARBA:ARBA00001933, CC ECO:0000256|PIRSR:PIRSR600183-50}; CC -!- PATHWAY: Amine and polyamine biosynthesis; putrescine biosynthesis via CC L-ornithine pathway; putrescine from L-ornithine: step 1/1. CC {ECO:0000256|ARBA:ARBA00034115}. CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-II family. CC {ECO:0000256|ARBA:ARBA00008872, ECO:0000256|RuleBase:RU003737}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:GLH87545.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BSCU01000026; GLH87545.1; -; Genomic_DNA. DR Proteomes; UP001161291; Unassembled WGS sequence. DR GO; GO:0003824; F:catalytic activity; IEA:InterPro. DR GO; GO:0006596; P:polyamine biosynthetic process; IEA:InterPro. DR CDD; cd00622; PLPDE_III_ODC; 1. DR Gene3D; 3.20.20.10; Alanine racemase; 1. DR InterPro; IPR009006; Ala_racemase/Decarboxylase_C. DR InterPro; IPR022643; De-COase2_C. DR InterPro; IPR022644; De-COase2_N. DR InterPro; IPR022653; De-COase2_pyr-phos_BS. DR InterPro; IPR000183; Orn/DAP/Arg_de-COase. DR InterPro; IPR002433; Orn_de-COase. DR InterPro; IPR029066; PLP-binding_barrel. DR PANTHER; PTHR11482; ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE; 1. DR PANTHER; PTHR11482:SF6; ORNITHINE DECARBOXYLASE 1-RELATED; 1. DR Pfam; PF02784; Orn_Arg_deC_N; 1. DR Pfam; PF00278; Orn_DAP_Arg_deC; 1. DR PRINTS; PR01179; ODADCRBXLASE. DR PRINTS; PR01182; ORNDCRBXLASE. DR SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1. DR SUPFAM; SSF51419; PLP-binding barrel; 1. DR PROSITE; PS00878; ODR_DC_2_1; 1. PE 3: Inferred from homology; KW Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR600183-50}. FT DOMAIN 30..262 FT /note="Orn/DAP/Arg decarboxylase 2 N-terminal" FT /evidence="ECO:0000259|Pfam:PF02784" FT DOMAIN 263..358 FT /note="Orn/DAP/Arg decarboxylase 2 C-terminal" FT /evidence="ECO:0000259|Pfam:PF00278" FT ACT_SITE 328 FT /note="Proton donor" FT /evidence="ECO:0000256|PIRSR:PIRSR600183-50" FT MOD_RES 51 FT /note="N6-(pyridoxal phosphate)lysine" FT /evidence="ECO:0000256|PIRSR:PIRSR600183-50" SQ SEQUENCE 380 AA; 41741 MW; 7816A0B9C2AA7233 CRC64; MTERIREFLR NRREEGLDHE PCLVVDLEIV RDNYMSFARA LPDSRVFYAV KANPAPEVLS LLASLGSSFD TATVAEIEMA LAAGATPDRI SYGNTIKKER DIARAYALGI RLFAVDCAAE VEKIARAAPG AKVFCRILYD CAGAEWPLSR KFGCDPEMAV DVLDLAKRLG LEPCGISFHV GSQQRKVKAW DRALAMASTV FRDCAERGIN LTMVNMGGGF PTKYLKDVPP VVQYGRSIFR ALRKHFGNQI PETIIEPGRG MVGNAGIIES EVVLISKKSD EDELRWVYLD IGKFGGLAET MDESIRYAIR TPHEGADMTP CVLAGPTCDS ADVMYEKLPY PLPVTLSIGD KVLIEGTGAY TSTYSSVAFN GIPPLKTYHI //