ID A0A9Q5YIM0_PISSA Unreviewed; 644 AA. AC A0A9Q5YIM0; DT 13-SEP-2023, integrated into UniProtKB/TrEMBL. DT 13-SEP-2023, sequence version 1. DT 27-MAR-2024, entry version 4. DE RecName: Full=Chaperone protein DnaK {ECO:0000256|ARBA:ARBA00014415, ECO:0000256|HAMAP-Rule:MF_00332}; DE AltName: Full=HSP70 {ECO:0000256|HAMAP-Rule:MF_00332}; DE AltName: Full=Heat shock 70 kDa protein {ECO:0000256|HAMAP-Rule:MF_00332}; DE AltName: Full=Heat shock protein 70 {ECO:0000256|HAMAP-Rule:MF_00332}; GN Name=dnaK {ECO:0000256|HAMAP-Rule:MF_00332, GN ECO:0000313|EMBL:QGO07276.1}; GN ORFNames=Psal009_03219 {ECO:0000313|EMBL:QGO07276.1}, Psal159_02825 GN {ECO:0000313|EMBL:QGP27048.1}; OS Piscirickettsia salmonis. OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales; OC Piscirickettsiaceae; Piscirickettsia. OX NCBI_TaxID=1238 {ECO:0000313|EMBL:QGO07276.1, ECO:0000313|Proteomes:UP000422232}; RN [1] {ECO:0000313|EMBL:QGO07276.1, ECO:0000313|Proteomes:UP000422232} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Psal-009 {ECO:0000313|EMBL:QGO07276.1, RC ECO:0000313|Proteomes:UP000422232}; RA Schober I., Bunk B., Sproer C., Carril G.P., Riedel T., RA Flores-Herrera P.A., Nourdin-Galindo G., Marshall S.H., Overmann J.; RT "Complete genome sequencing of Piscirickettsia salmonis strain Psal-009."; RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:QGP27048.1, ECO:0000313|Proteomes:UP000818417} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Psal-159 {ECO:0000313|EMBL:QGP27048.1, RC ECO:0000313|Proteomes:UP000818417}; RA Schober I., Bunk B., Sproer C., Carril G.P., Riedel T., RA Flores-Herrera P.A., Nourdin-Galindo G., Marshall S.H., Overmann J.; RT "Complete genome sequencing of Piscirickettsia salmonis strain Psal-159."; RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Acts as a chaperone. {ECO:0000256|HAMAP-Rule:MF_00332}. CC -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000256|HAMAP- CC Rule:MF_00332}. CC -!- SIMILARITY: Belongs to the heat shock protein 70 family. CC {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|HAMAP-Rule:MF_00332, CC ECO:0000256|RuleBase:RU003322}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP038908; QGO07276.1; -; Genomic_DNA. DR EMBL; CP039186; QGP27048.1; -; Genomic_DNA. DR RefSeq; WP_016210369.1; NZ_PDFD01000036.1. DR GeneID; 66742146; -. DR Proteomes; UP000422232; Chromosome. DR Proteomes; UP000818417; Chromosome. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro. DR GO; GO:0051082; F:unfolded protein binding; IEA:InterPro. DR Gene3D; 1.20.1270.10; -; 1. DR Gene3D; 3.30.420.40; -; 2. DR HAMAP; MF_00332; DnaK; 1. DR InterPro; IPR043129; ATPase_NBD. DR InterPro; IPR012725; Chaperone_DnaK. DR InterPro; IPR018181; Heat_shock_70_CS. DR InterPro; IPR029048; HSP70_C_sf. DR InterPro; IPR029047; HSP70_peptide-bd_sf. DR InterPro; IPR013126; Hsp_70_fam. DR NCBIfam; TIGR02350; prok_dnaK; 1. DR PANTHER; PTHR19375:SF541; CHAPERONE PROTEIN DNAK; 1. DR PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1. DR Pfam; PF00012; HSP70; 1. DR PRINTS; PR00301; HEATSHOCK70. DR SUPFAM; SSF53067; Actin-like ATPase domain; 2. DR SUPFAM; SSF100934; Heat shock protein 70kD (HSP70), C-terminal subdomain; 1. DR SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1. DR PROSITE; PS00297; HSP70_1; 1. DR PROSITE; PS00329; HSP70_2; 1. PE 2: Evidence at transcript level; KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP- KW Rule:MF_00332}; KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|HAMAP-Rule:MF_00332}; KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP- KW Rule:MF_00332}; KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|HAMAP- KW Rule:MF_00332}; KW Stress response {ECO:0000256|ARBA:ARBA00023016, ECO:0000256|HAMAP- KW Rule:MF_00332}. FT REGION 610..644 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT MOD_RES 198 FT /note="Phosphothreonine; by autocatalysis" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00332" SQ SEQUENCE 644 AA; 68868 MW; 07D5EDE891C64A04 CRC64; MAKIIGIDLG TTNSCVAVLD GDKPRVIESA EGDRTTPSIV AYTNDGVTVG QPAKRQAVTN PNNTLFAVKR LIGRKFSDDT VQRDIERLPY TIAAADNGDA WIDVNGEKLA PPQISAQVLA KMKKTAEDYL GEDVKEAVIT VPAYFNDAQR QATKDAGRIA GLDVKRIINE PTAAALAYGM DKKRGDGVIA VYDLGGGTFD ISIIEIAEVD GEHQFEVLAT NGDTHLGGED FDLRLISYLV DEFKKEQGID LNNDPLALQR LKEAAEKAKI ELSSTQQTDV NLPYITADAT GPKHMNIRVT RAKFESLVED LVEGTIEPCR VALKDAGLSV SDVTDVILVG GQTRMPKAQE VVKNFFGKEP RRDVNPDEAV AVGAAIQGGV LAGDVKDVLL LDVTPLSLGI ETMGGVMTKL IEKNTTIPTK ASQTFSTAQD NQTAVTVHVL QGEREVATGN KSLGRFDLAD IPPAPRGMPQ VEVTFDIDAN GILNVSAKDK GTGKEQSIVI RASSGLSDDE VDAMIKDAED HADDDKKFQE LVGARNNAEA MIHATEKGLK EAGDKVAADD KTAIEKAISE LKDVVSGNDK AVIDEKVEAL TQASAKMAEV LYANQGAEAE AAAAAGAEQA QSQTDEKKDD DVVDAEFEEV KDKK //