ID A0A978VVL9_ZIZJJ Unreviewed; 891 AA. AC A0A978VVL9; DT 22-FEB-2023, integrated into UniProtKB/TrEMBL. DT 22-FEB-2023, sequence version 1. DT 29-MAY-2024, entry version 8. DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU364117}; DE EC=5.6.2.4 {ECO:0000256|RuleBase:RU364117}; GN ORFNames=FEM48_Zijuj02G0120500 {ECO:0000313|EMBL:KAH7542864.1}; OS Ziziphus jujuba var. spinosa. OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC rosids; fabids; Rosales; Rhamnaceae; Paliureae; Ziziphus. OX NCBI_TaxID=714518 {ECO:0000313|EMBL:KAH7542864.1, ECO:0000313|Proteomes:UP000813462}; RN [1] {ECO:0000313|EMBL:KAH7542864.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=AT0 {ECO:0000313|EMBL:KAH7542864.1}; RC TISSUE=Leaf {ECO:0000313|EMBL:KAH7542864.1}; RA Shen L.-Y., Luo H., Wang X.-L., Wang X.-M., Qiu X.-J., Liu H., Zhou S.-S., RA Jia K.-H., Nie S., Bao Y.-T., Zhang R.-G., Yun Q.-Z., Chai Y.-H., Lu J.-Y., RA Li Y., Zhao S.-W., Mao J.-F., Jia S.-G., Mao Y.-M.; RT "Chromosome-Scale Genome Assembly for Chinese Sour Jujube and Insights Into RT Its Genome Evolution and Domestication Signature."; RL Front. Plant Sci. 0:0-0(2021). CC -!- CATALYTIC ACTIVITY: CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065, CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; CC Evidence={ECO:0000256|RuleBase:RU364117}; CC -!- CATALYTIC ACTIVITY: CC Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by CC translocating in the 3'-5' direction.; EC=5.6.2.4; CC Evidence={ECO:0000256|ARBA:ARBA00034617, CC ECO:0000256|RuleBase:RU364117}; CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU364117}. CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily. CC {ECO:0000256|ARBA:ARBA00005446, ECO:0000256|RuleBase:RU364117}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:KAH7542864.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JAEACU010000002; KAH7542864.1; -; Genomic_DNA. DR Proteomes; UP000813462; Unassembled WGS sequence. DR GO; GO:0005694; C:chromosome; IEA:TreeGrafter. DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter. DR GO; GO:0005654; C:nucleoplasm; IEA:TreeGrafter. DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0009378; F:four-way junction helicase activity; IEA:TreeGrafter. DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro. DR GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:TreeGrafter. DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:TreeGrafter. DR GO; GO:0044806; P:G-quadruplex DNA unwinding; IEA:TreeGrafter. DR GO; GO:0000723; P:telomere maintenance; IEA:TreeGrafter. DR CDD; cd17920; DEXHc_RecQ; 1. DR CDD; cd18794; SF2_C_RecQ; 1. DR Gene3D; 1.10.150.80; HRDC domain; 1. DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2. DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1. DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom. DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ. DR InterPro; IPR014001; Helicase_ATP-bd. DR InterPro; IPR001650; Helicase_C-like. DR InterPro; IPR029491; Helicase_HTH. DR InterPro; IPR010997; HRDC-like_sf. DR InterPro; IPR002121; HRDC_dom. DR InterPro; IPR044876; HRDC_dom_sf. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR032284; RecQ_Zn-bd. DR InterPro; IPR018982; RQC_domain. DR InterPro; IPR036388; WH-like_DNA-bd_sf. DR NCBIfam; TIGR00614; recQ_fam; 1. DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1. DR PANTHER; PTHR13710:SF120; WERNER SYNDROME ATP-DEPENDENT HELICASE; 1. DR Pfam; PF00270; DEAD; 1. DR Pfam; PF00271; Helicase_C; 1. DR Pfam; PF00570; HRDC; 1. DR Pfam; PF14493; HTH_40; 1. DR Pfam; PF16124; RecQ_Zn_bind; 1. DR Pfam; PF09382; RQC; 1. DR SMART; SM00487; DEXDc; 1. DR SMART; SM00490; HELICc; 1. DR SMART; SM00956; RQC; 1. DR SUPFAM; SSF47819; HRDC-like; 1. DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2. DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1. DR PROSITE; PS51194; HELICASE_CTER; 1. DR PROSITE; PS50967; HRDC; 1. PE 3: Inferred from homology; KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU364117}; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}; KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|RuleBase:RU364117}; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU364117}; KW Isomerase {ECO:0000256|ARBA:ARBA00023235}; KW Magnesium {ECO:0000256|ARBA:ARBA00022842}; KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, KW ECO:0000256|RuleBase:RU364117}; Nucleus {ECO:0000256|RuleBase:RU364117}; KW Reference proteome {ECO:0000313|Proteomes:UP000813462}. FT DOMAIN 22..154 FT /note="Helicase ATP-binding" FT /evidence="ECO:0000259|PROSITE:PS51192" FT DOMAIN 185..336 FT /note="Helicase C-terminal" FT /evidence="ECO:0000259|PROSITE:PS51194" FT DOMAIN 515..595 FT /note="HRDC" FT /evidence="ECO:0000259|PROSITE:PS50967" SQ SEQUENCE 891 AA; 99888 MW; 875C96DD0FE43F3F CRC64; MESLLKQYFG YSAFRPYQKE VIEKIINKRD CLVVMATGSG KSLCYQIPPL AVGTTGIVVS PLISLMQDQV MSLKQRGIKA EFLGSTQTDQ SVYTKAQSGE FHILFMTPEK ACMVSKSFWS NLLKVGICLF AVDEAHCISE WGHSFRVRND IISSLKMKDP YVAIGSFDRQ NLFYGVKSFN RGQSSVDELV QEISKFVAST SSTIVYCTTR NDVEQIYKSL QEAGIKAAIY HGQMGNKARE ESHRLFITDE LHVMVATIAF GMGIDKPNVR QVIHYGCPKS LESYYQESGR CGRDGMASVC WLYYTRSDFA KADFYIGELQ TENQRKAVVE SLMAAQHYCL LTTCRRKFLL NHFGENLSAA KCENCDNCII SRRERDMSRE AFLLMACIQS CKGRWGLNMP VDILRGSRSK KVLDAHSDKL PLYGLGKGYS SNWWKALAYT LISSGYLMET VVDIYKTVSV SPKGVQYLSS ATPDYQPPLV LPVTNEMVAE EGNISQSSEA GELKKLSTLE SEGFSEAEEQ LYHMLLEERM KLARGVGTAP YAICGDQTIK KIALTRPSTK ARLANIDGVN QTMTSSGSPF VLNLMLTIKY LLMTHGNHVL QTIEHLSRQL NLSLDGEASI QTATTRKVYP VPSQHRKLTQ AKFVAWQMWH EDGLSVQKIA NNPARPSPIK EQTVTEYLLE AAQEGFAMDW TRFCAEVGLT LEMFSDIKGA ILKVGSTEKL KPIKNELSED INYTHIKTCL AMHNCGITPE VVLSGSKASG LPKSSLNACC KETPCEVKTT NQNLVPCLEE NEETASLPFN EFQEAELPLI HDTDLLPKKR QKVSEPEKRG TMELNATEDS ILDWLKNYEG VTLSDIVKHF SGSEEQFVSD LVNQLEGEFF IYKKNNVYKL M //