ID A0A925YQK4_9HYPH Unreviewed; 195 AA. AC A0A925YQK4; DT 22-FEB-2023, integrated into UniProtKB/TrEMBL. DT 22-FEB-2023, sequence version 1. DT 24-JAN-2024, entry version 4. DE SubName: Full=3,4-dihydroxy-2-butanone-4-phosphate synthase {ECO:0000313|EMBL:MBC8036410.1}; GN ORFNames=H7X89_04255 {ECO:0000313|EMBL:MBC8036410.1}; OS Hyphomicrobiales bacterium. OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales. OX NCBI_TaxID=1909294 {ECO:0000313|EMBL:MBC8036410.1, ECO:0000313|Proteomes:UP000609450}; RN [1] {ECO:0000313|EMBL:MBC8036410.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=ES-bin-180 {ECO:0000313|EMBL:MBC8036410.1}; RA Zeng Y.; RT "Metagenome-assembled genomes from the Lille Firn glacier at the Villum RT Research Station in northeast Greenland."; RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases. CC -!- PATHWAY: Cofactor biosynthesis; riboflavin biosynthesis. CC {ECO:0000256|ARBA:ARBA00005104}. CC -!- SIMILARITY: In the C-terminal section; belongs to the GTP CC cyclohydrolase II family. {ECO:0000256|ARBA:ARBA00008976}. CC -!- SIMILARITY: In the N-terminal section; belongs to the DHBP synthase CC family. {ECO:0000256|ARBA:ARBA00005520}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:MBC8036410.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JACMJT010000162; MBC8036410.1; -; Genomic_DNA. DR Proteomes; UP000609450; Unassembled WGS sequence. DR GO; GO:0003824; F:catalytic activity; IEA:UniProt. DR GO; GO:0009231; P:riboflavin biosynthetic process; IEA:UniProtKB-KW. DR Gene3D; 3.90.870.10; DHBP synthase; 1. DR Gene3D; 3.40.50.10990; GTP cyclohydrolase II; 1. DR InterPro; IPR017945; DHBP_synth_RibB-like_a/b_dom. DR InterPro; IPR032677; GTP_cyclohydro_II. DR InterPro; IPR036144; RibA-like_sf. DR PANTHER; PTHR21327:SF18; 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE; 1. DR PANTHER; PTHR21327; GTP CYCLOHYDROLASE II-RELATED; 1. DR Pfam; PF00925; GTP_cyclohydro2; 1. DR SUPFAM; SSF142695; RibA-like; 1. DR SUPFAM; SSF55821; YrdC/RibB; 1. PE 3: Inferred from homology; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW Riboflavin biosynthesis {ECO:0000256|ARBA:ARBA00022619}. FT DOMAIN 46..191 FT /note="GTP cyclohydrolase II" FT /evidence="ECO:0000259|Pfam:PF00925" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:MBC8036410.1" SQ SEQUENCE 195 AA; 21342 MW; 0B1F798A1511DC20 CRC64; VNDDGSVKRG PQVLAFAREH GFKIISVADL IAHRQKRERL VEQTGQFDVA TVIGTARGFS YVTPFDAVEQ LALVYGDISG GKNIPVRLHR ENVLEDVFGN RHTLEAVFDI FKKQGRGILV YLQEGTAGVP ASQMAAEKVG SAARREQSWR DVGLGAQILR DLNVSSIRLI SSSNRHYVGL AGFGIEIAET IRIGE //