ID A0A8V0Y8J4_CHICK Unreviewed; 1028 AA. AC A0A8V0Y8J4; DT 14-DEC-2022, integrated into UniProtKB/TrEMBL. DT 14-DEC-2022, sequence version 1. DT 29-MAY-2024, entry version 9. DE RecName: Full=Nck-associated protein 1 {ECO:0000256|ARBA:ARBA00039689}; GN Name=NCKAP1 {ECO:0000313|Ensembl:ENSGALP00010015278.1}; OS Gallus gallus (Chicken). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; OC Phasianinae; Gallus. OX NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010015278.1, ECO:0000313|Proteomes:UP000000539}; RN [1] {ECO:0000313|Ensembl:ENSGALP00010015278.1} RP IDENTIFICATION. RC STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010015278.1}; RG Ensembl; RL Submitted (FEB-2024) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00037856}; CC Single-pass membrane protein {ECO:0000256|ARBA:ARBA00037856}; CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00037856}. Cell projection, CC lamellipodium membrane {ECO:0000256|ARBA:ARBA00037839}; Single-pass CC membrane protein {ECO:0000256|ARBA:ARBA00037839}; Cytoplasmic side CC {ECO:0000256|ARBA:ARBA00037839}. CC -!- SIMILARITY: Belongs to the HEM-1/HEM-2 family. CC {ECO:0000256|ARBA:ARBA00037947}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR Ensembl; ENSGALT00010026805.1; ENSGALP00010015278.1; ENSGALG00010011212.1. DR GeneTree; ENSGT00390000016619; -. DR Proteomes; UP000000539; Chromosome 7. DR GO; GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell. DR GO; GO:0031209; C:SCAR complex; IEA:TreeGrafter. DR GO; GO:0016477; P:cell migration; IEA:TreeGrafter. DR GO; GO:0030031; P:cell projection assembly; IEA:TreeGrafter. DR GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:TreeGrafter. DR GO; GO:0048812; P:neuron projection morphogenesis; IEA:TreeGrafter. DR InterPro; IPR019137; Nck-associated_protein-1. DR PANTHER; PTHR12093; NCK-ASSOCIATED PROTEIN 1; 1. DR PANTHER; PTHR12093:SF11; NCK-ASSOCIATED PROTEIN 1; 1. DR Pfam; PF09735; Nckap1; 1. PE 1: Evidence at protein level; KW Cell membrane {ECO:0000256|ARBA:ARBA00022475}; KW Cell projection {ECO:0000256|ARBA:ARBA00023273}; KW Membrane {ECO:0000256|ARBA:ARBA00023136}; KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A8V0Y8J4}; KW Reference proteome {ECO:0000313|Proteomes:UP000000539}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}. FT REGION 540..565 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 547..565 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 1028 AA; 117302 MW; 456C460FA6BEE50A CRC64; MEFKDHVCEL LNTIDVCQVF FDITVNFDLT KNYLDLIITY TTLMILLSRI EERKAIIGLY NYAHEMTHGA SDREYPRLGQ MIVDYENPLK KMMEEFVPHS KSLSDALISL QMVYPRRNLS ADQWRNAQLL SLISAPSTML NPAQSDTMPC EYLSLDAMEK WIIFGFILCH GVLNSDATAL NLWKLALQSS SCLALFRDEV FHIHKAAEDL FVNIRGYNKR INDIRECKEA AVSHAGSMHR ERRKFLRSAL KELATVLSDQ PGLLGPKALF VFMALSFARD EIIWLLRHAD NMPKKSADDF IDKHIAELIF YMEELRAHVR KYGPVMQRYY VQYLSGFDAV VLNELVQNLS VCPEDESIIM SSFVNTMTSL SVKQVEDGEV FDFRGMRLDW FRLQAYTSVS KASLGLADHR ELGKMMNTII FHTKMVDSLV EMLVETSDLS IFCFYSRAFE KMFQQCLELP SQSRYSIAFP LLCTHFMSCT HELCPEERHH IGDRSLSLCN MFLDEMAKQA RNLITDICTE QCTLSDQLLP KHCAKTISQA VNKKSKKQTG KKGEPEREKP GVESMRKNRL VVTNLDKLHT ALSELCFSIN YVPNMVVWEH TFTPREYLTS HLEIRFTKSI VGMTMYNQAT QEIAKPSELL TSVRAYMTVL QSIENYVQID ITRVFNNVLL QQTQHLDSHG EPTITSLYTN WYLETLLRQV SNGHIAYFPA MKAFVNLPTE NELTFNAEEY SDISEMRALS ELLGPYGMKF LSESLMWHIS SQVAELKKLV VENVEVLTQM RTSFDKPDQM AALFKRLSSV DSVLKRMTII GVILSFRSLA QEALRDVLSY HIPFLVSSIE DFKDHIPRET DMKVAMNVYE LSSAAGLPCE IDPALVVALS SQKSENISPE EEYKIACLLM VFVAVSLPTL ASNVMSQYSP AIEGHCNNIH CLAKAINQIA AALFTIHKGS IEDRLKEFLA LASSSLLKIG QETDKTTTRN RESVYLLLDM IVQESPFLTM DLLESCFPYV LLRNAYHAVY KQSVTSSA //