ID A0A8T0ZRL9_9STRA Unreviewed; 1392 AA. AC A0A8T0ZRL9; DT 12-OCT-2022, integrated into UniProtKB/TrEMBL. DT 12-OCT-2022, sequence version 1. DT 24-JAN-2024, entry version 5. DE RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; DE EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273}; GN ORFNames=PC113_g4414 {ECO:0000313|EMBL:KAG2864614.1}; OS Phytophthora cactorum. OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae; OC Phytophthora. OX NCBI_TaxID=29920 {ECO:0000313|EMBL:KAG2864614.1, ECO:0000313|Proteomes:UP000735874}; RN [1] {ECO:0000313|EMBL:KAG2864614.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=15-7 {ECO:0000313|EMBL:KAG2864614.1}; RA Armitage A.D., Nellist C.F., Bates H., Vickerstaff R.J., Harrison R.J.; RT "Effector identification in a new, highly contiguous assembly of the RT strawberry crown rot pathogen Phytophthora cactorum."; RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA- CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474, CC ChEBI:CHEBI:61977; EC=3.1.3.16; CC Evidence={ECO:0000256|RuleBase:RU004273}; CC -!- COFACTOR: CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035; CC Evidence={ECO:0000256|ARBA:ARBA00001936}; CC -!- SIMILARITY: Belongs to the PPP phosphatase family. CC {ECO:0000256|ARBA:ARBA00008294, ECO:0000256|RuleBase:RU004273}. CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS8 family. CC {ECO:0000256|ARBA:ARBA00006471}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:KAG2864614.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; RCMG01000076; KAG2864614.1; -; Genomic_DNA. DR Proteomes; UP000735874; Unassembled WGS sequence. DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW. DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW. DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro. DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro. DR GO; GO:0006412; P:translation; IEA:InterPro. DR Gene3D; 3.30.1370.30; -; 1. DR Gene3D; 3.30.1490.10; -; 1. DR Gene3D; 3.60.21.10; -; 1. DR Gene3D; 1.10.238.10; EF-hand; 2. DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1. DR HAMAP; MF_01302_A; Ribosomal_S8_A; 1. DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH. DR InterPro; IPR011992; EF-hand-dom_pair. DR InterPro; IPR018247; EF_Hand_1_Ca_BS. DR InterPro; IPR002048; EF_hand_dom. DR InterPro; IPR029052; Metallo-depent_PP-like. DR InterPro; IPR000630; Ribosomal_uS8. DR InterPro; IPR047863; Ribosomal_uS8_CS. DR InterPro; IPR035987; Ribosomal_uS8_sf. DR InterPro; IPR001751; S100/CaBP7/8-like_CS. DR InterPro; IPR006186; Ser/Thr-sp_prot-phosphatase. DR InterPro; IPR000306; Znf_FYVE. DR InterPro; IPR017455; Znf_FYVE-rel. DR InterPro; IPR011011; Znf_FYVE_PHD. DR InterPro; IPR013083; Znf_RING/FYVE/PHD. DR PANTHER; PTHR45668:SF5; SERINE/THREONINE-PROTEIN PHOSPHATASE 5; 1. DR PANTHER; PTHR45668; SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED; 1. DR Pfam; PF13499; EF-hand_7; 1. DR Pfam; PF01363; FYVE; 1. DR Pfam; PF00149; Metallophos; 1. DR Pfam; PF00410; Ribosomal_S8; 1. DR PRINTS; PR00114; STPHPHTASE. DR SMART; SM00054; EFh; 4. DR SMART; SM00064; FYVE; 1. DR SMART; SM00156; PP2Ac; 1. DR SUPFAM; SSF47473; EF-hand; 2. DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1. DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1. DR SUPFAM; SSF56047; Ribosomal protein S8; 1. DR PROSITE; PS00018; EF_HAND_1; 2. DR PROSITE; PS50222; EF_HAND_2; 4. DR PROSITE; PS00053; RIBOSOMAL_S8; 1. DR PROSITE; PS00303; S100_CABP; 1. DR PROSITE; PS00125; SER_THR_PHOSPHATASE; 1. DR PROSITE; PS50178; ZF_FYVE; 1. PE 3: Inferred from homology; KW Calcium {ECO:0000256|ARBA:ARBA00022837}; KW Hydrolase {ECO:0000256|RuleBase:RU004273}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274}; KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980}; KW Zinc {ECO:0000256|ARBA:ARBA00022833}; KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE- KW ProRule:PRU00091}. FT DOMAIN 168..223 FT /note="FYVE-type" FT /evidence="ECO:0000259|PROSITE:PS50178" FT DOMAIN 746..781 FT /note="EF-hand" FT /evidence="ECO:0000259|PROSITE:PS50222" FT DOMAIN 925..960 FT /note="EF-hand" FT /evidence="ECO:0000259|PROSITE:PS50222" FT DOMAIN 989..1024 FT /note="EF-hand" FT /evidence="ECO:0000259|PROSITE:PS50222" FT DOMAIN 1124..1159 FT /note="EF-hand" FT /evidence="ECO:0000259|PROSITE:PS50222" FT REGION 865..896 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 1392 AA; 159027 MW; 4B489497B5B4916A CRC64; MDTEGFTSRA WLGHWVSGEE EPVNNYYEDH KLMEGALIKL GDYAHFRYFL LFRNGRFCYY ELPMPAAAPG GASEGPRRVH LTLTSKHLRG VMMLNASVNA KDLAKSEDEY DADLIKRGLV FNRKKLEMQL TGYSPTGQLM CWKLRAGKDA VYLKWERAFR LALRPIWVQN SKCCMVCKKE FSFFIRPHHC RKCGTCMCDE CSVFVPRLPM QGYYDEVRIC RDCSPIKIQR SSLKMGTRVL VYGILVGRVV QVDAADDSVD GSAFVNVELV KKNNQLRRFA LEHVELYSDA VLSANRIKNA IRQHLSYAVF RTQLNFNTWN LLETVQEQRT VQMVRILNKS TSINELQSMV PMLGSLDTMQ FPDDDVSEKD RVKESLSHYR GVHVSFPLRL DTVKKLINQF RNGILLHRVF VRQILDESEK LFRKMHDSPM NEIEIPMGVQ LVVVGDLHGQ LEDLLTIMDK NGVPNSKTWY LFNGDFVDRG SHGIEVILLL LIFKLLYPHY VFLNRGNHEE RMINEVFGFE DEVYTKYGTD NDEVAGWSGL GTSMNYSPMK LFQMFETVFG LFPIFALLNK RVFIVHGGLS NHENVTIEEL LQLDHRREIP TQGTSRADEV FTHLLWSDPR DEDGWKPSSR GAGVEFGPDI TKAFCSQNGI SLIIRSHECR EEGFDIVHDG LLLTVFSASS YCGSQTNKGA YVQLELGDDN EVKPHVVQFS SQPLQKLKDA GRNEWRKKAQ RLERRTLMSL VEIICEKKHA LLSAFNELDT AGSGRVTKLE WKATLQKVLG IEASFLSYFH QLAEEEQDGG VDYQKFLNRY TVELDSGNVE WRRNLIRKVW KGFCQALPHP SESDAEKMTL QDKLHFAFNL FQSSPPGAAK KEQAATSLSK IDENGPPSTP AYGEKSKGSY MHTGLVTYEV FRNTIQDKLQ LGDTLSEQQI FELMQHLDQN HDGVVDYQEF CSFFAEFSRT DYLQEIFEVD DTKAISLLNR CAALLQRPNK FKSLREAFDA FDHSKTGRLT VDDILKGTQE LNMVPELDNE EAQLLFNSIL LSYYGINQRH QWDTRGLDWV VFEDTFSPDS TFQRRLWLAS LGASNTNLAA LDITEDDVVQ DGQSSRNQAW ADTFVDSVKQ SLHEQRLYIK FLFRILDRKR HGYVTKQQFV ATMQAINEEH GAPLKLAQLE QLADAFAHRK TVRRMSNAGE ETEETRKYVS YPEFLRSLRI IDSGPTDGIA ASPEMQEATD ASSGEQLSCS GGRSFANLSP VFSKPTPPPL ATMVRMSVLA DCLKTMYNAE KRGKRQVLIR PSSKVIVKFL QVMQKNGYIG EFEIVDDHRA GKIVVELKGR INKCGVISPR FDVKLADYEK WINNLLPSRQ FGHIVVSTTY GIMDHHEARR KHTGGKIIGF FY //