ID   A0A8M9QB78_DANRE        Unreviewed;       326 AA.
AC   A0A8M9QB78;
DT   03-AUG-2022, integrated into UniProtKB/TrEMBL.
DT   03-AUG-2022, sequence version 1.
DT   03-MAY-2023, entry version 5.
DE   SubName: Full=Troponin T2e, cardiac isoform X1 {ECO:0000313|RefSeq:XP_021330700.1};
GN   Name=tnnt2e {ECO:0000313|RefSeq:XP_021330700.1};
GN   Synonyms=si:ch211-136g2.1 {ECO:0000313|RefSeq:XP_021330700.1};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|Proteomes:UP000000437, ECO:0000313|RefSeq:XP_021330700.1};
RN   [1] {ECO:0000313|RefSeq:XP_021330700.1}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|RefSeq:XP_021330700.1};
RG   RefSeq;
RL   Submitted (JAN-2023) to UniProtKB.
CC   -!- FUNCTION: Troponin T is the tropomyosin-binding subunit of troponin,
CC       the thin filament regulatory complex which confers calcium-sensitivity
CC       to striated muscle actomyosin ATPase activity.
CC       {ECO:0000256|ARBA:ARBA00003363}.
CC   -!- SIMILARITY: Belongs to the troponin T family.
CC       {ECO:0000256|ARBA:ARBA00008330}.
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DR   RefSeq; XP_021330700.1; XM_021475025.1.
DR   Proteomes; UP000000437; Chromosome 4.
DR   GO; GO:0005861; C:troponin complex; IEA:InterPro.
DR   GO; GO:0006937; P:regulation of muscle contraction; IEA:InterPro.
DR   Gene3D; 1.20.5.350; -; 1.
DR   InterPro; IPR027707; TNNT.
DR   InterPro; IPR001978; Troponin.
DR   InterPro; IPR038077; Troponin_sf.
DR   PANTHER; PTHR11521:SF20; NOVEL SLOW SKELETAL TROPONIN T FAMILY PROTEIN-RELATED; 1.
DR   PANTHER; PTHR11521; TROPONIN T; 1.
DR   Pfam; PF00992; Troponin; 1.
DR   SUPFAM; SSF90250; Troponin coil-coiled subunits; 1.
PE   1: Evidence at protein level;
KW   Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW   Proteomics identification {ECO:0007829|PeptideAtlas:A0A8M9QB78};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT   REGION          1..91
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          125..214
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..56
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        125..177
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        192..214
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   326 AA;  38828 MW;  BE0DC893A7F88BDD CRC64;
     MADTEDVVEE EVQEVEETEE EVEVPPPTEE EPAPEVEEPP EVEEEPEPEP QEAPVAEEVT
     DETKPKPKFM PNISAPKIPE GDKVDFDDIH RKRQEKDLSE LQSLIEAHFI QRKKDEEELI
     ALVNRIEKRR GERAEQQRIR AEKEKERQAR LAEEKERREQ EEQRKKHDED AKKKKALTNM
     THQYGGIQQK GDGRKGAKKQ TEREKKKKIL AERKKPLNID HLSEDKLKEK ASEMWQWMMQ
     LEAEKFDLSE KLKRQKYDCQ RSWQGQGWRQ AEVNARRIQE LQRSRRLYLL HHIQLKSELL
     ALLNYFLPPC IFLICPNFCL TERFYF
//