ID   A0A8M9PZI9_DANRE        Unreviewed;       630 AA.
AC   A0A8M9PZI9;
DT   03-AUG-2022, integrated into UniProtKB/TrEMBL.
DT   03-AUG-2022, sequence version 1.
DT   14-DEC-2022, entry version 3.
DE   RecName: Full=phosphoenolpyruvate carboxykinase (GTP) {ECO:0000256|ARBA:ARBA00012306};
DE            EC=4.1.1.32 {ECO:0000256|ARBA:ARBA00012306};
GN   Name=pck1 {ECO:0000313|RefSeq:XP_021332473.1};
GN   Synonyms=cb856 {ECO:0000313|RefSeq:XP_021332473.1}, cb924
GN   {ECO:0000313|RefSeq:XP_021332473.1}, fj93h11
GN   {ECO:0000313|RefSeq:XP_021332473.1}, wu:fc51c05
GN   {ECO:0000313|RefSeq:XP_021332473.1}, wu:fj93h11
GN   {ECO:0000313|RefSeq:XP_021332473.1}, zgc:63869
GN   {ECO:0000313|RefSeq:XP_021332473.1};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|Proteomes:UP000000437, ECO:0000313|RefSeq:XP_021332473.1};
RN   [1] {ECO:0000313|RefSeq:XP_021332473.1}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|RefSeq:XP_021332473.1};
RG   RefSeq;
RL   Submitted (APR-2022) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|ARBA:ARBA00001936};
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC       {ECO:0000256|ARBA:ARBA00004742}.
CC   -!- SIMILARITY: Belongs to the phosphoenolpyruvate carboxykinase [GTP]
CC       family. {ECO:0000256|ARBA:ARBA00005796}.
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DR   RefSeq; XP_021332473.1; XM_021476798.1.
DR   SMR; A0A8M9PZI9; -.
DR   UniPathway; UPA00138; -.
DR   Proteomes; UP000000437; Chromosome 6.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004613; F:phosphoenolpyruvate carboxykinase (GTP) activity; IEA:InterPro.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR   CDD; cd00819; PEPCK_GTP; 1.
DR   Gene3D; 3.40.449.10; -; 1.
DR   Gene3D; 3.90.228.20; -; 1.
DR   HAMAP; MF_00452; PEPCK_GTP; 1.
DR   InterPro; IPR018091; PEP_carboxykin_GTP_CS.
DR   InterPro; IPR013035; PEP_carboxykinase_C.
DR   InterPro; IPR008209; PEP_carboxykinase_GTP.
DR   InterPro; IPR035077; PEP_carboxykinase_GTP_C.
DR   InterPro; IPR035078; PEP_carboxykinase_GTP_N.
DR   InterPro; IPR008210; PEP_carboxykinase_N.
DR   PANTHER; PTHR11561; PHOSPHOENOLPYRUVATE CARBOXYKINASE; 1.
DR   Pfam; PF00821; PEPCK_GTP; 1.
DR   Pfam; PF17297; PEPCK_N; 1.
DR   PIRSF; PIRSF001348; PEP_carboxykinase_GTP; 1.
DR   SUPFAM; SSF68923; PEP carboxykinase N-terminal domain; 1.
DR   PROSITE; PS00505; PEPCK_GTP; 1.
PE   3: Inferred from homology;
KW   Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Manganese {ECO:0000256|ARBA:ARBA00023211};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT   DOMAIN          29..257
FT                   /note="PEPCK_N"
FT                   /evidence="ECO:0000259|Pfam:PF17297"
FT   DOMAIN          261..619
FT                   /note="PEPCK_GTP"
FT                   /evidence="ECO:0000259|Pfam:PF00821"
SQ   SEQUENCE   630 AA;  69721 MW;  88E31B9C3012D8AA CRC64;
     MPPQLQSQDR SCPRVLQGDL ASLSASVREF IDSSVSLCQP DALHICDGSE QENSTILSLL
     EEQGAIKRLR KYSNCWLART DPRDVARVES KTVIVTAEQR DTVPTPTGGG VSQLGRWMCP
     EEWDKAMNLR FPGCMKGRVM YVIPFSMGPV GSPLSKIGVE LTDSPYVVAS MRIMTRMGKT
     VLSALGNGEF VRCLHSVGCP LPLRKPLVNN WPCNPELTLV AHIPDQRKIV SFGSGYGGNS
     LLGKKCFALR IASRIAKEEG WLAEHMLILG ITNPAGQKKY FAAAFPSACG KTNLAMLKPS
     LPGWKVECVG DDIAWMKFDK EGNLRAINPE NGFFGVAPGT SSKTNPNAMS TISCNTLFTN
     VAESSDGGVF WEGMDEDLPE GVTLTSWKNQ PWTPEDGEPC AHPNSRFCTP AAQCPIIDPQ
     WESPEGVPIE AIIFGGRRPQ GVPLVYEAFD WAHGVFVGAS MRSEATAAAE HKGKVIMHDP
     FAMRPFFGYN FGQYLSHWLS MEQRPGAKLP KIFHVNWFGR SSSGRFLWPG FGENIRVLEW
     MFGRLSGGAE ARTTAVGLVP ADGALNLHGL PDVEPLELFR VSQEFWMQEL QEIREYFSRE
     LNRDLPQEMQ RQLELLEHRL THTHVSSKHG
//