ID A0A8M3B7X0_DANRE Unreviewed; 783 AA. AC A0A8M3B7X0; DT 03-AUG-2022, integrated into UniProtKB/TrEMBL. DT 03-AUG-2022, sequence version 1. DT 02-OCT-2024, entry version 13. DE SubName: Full=Kin of IRRE like b isoform X6 {ECO:0000313|RefSeq:XP_009297041.1}; GN Name=kirrel1b {ECO:0000313|ZFIN:ZDB-GENE-070912-173}; GN Synonyms=kirrelb {ECO:0000313|RefSeq:XP_009297041.1}, GN si:ch211-195h23.2 {ECO:0000313|RefSeq:XP_009297041.1}; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Danionidae; Danioninae; Danio. OX NCBI_TaxID=7955 {ECO:0000313|Proteomes:UP000000437, ECO:0000313|RefSeq:XP_009297041.1}; RN [1] {ECO:0000313|Proteomes:UP000000437} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=23594743; DOI=10.1038/nature12111; RG Genome Reference Consortium Zebrafish; RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J., RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D., RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B., RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J., RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D., RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B., RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P., RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., RA Rogers J., Stemple D.L.; RT "The zebrafish reference genome sequence and its relationship to the human RT genome."; RL Nature 496:498-503(2013). RN [2] {ECO:0000313|RefSeq:XP_009297041.1} RP IDENTIFICATION. RC STRAIN=Tuebingen {ECO:0000313|RefSeq:XP_009297041.1}; RG RefSeq; RL Submitted (JUN-2024) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single- CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; XP_009297041.1; XM_009298766.3. DR GeneID; 100170816; -. DR AGR; ZFIN:ZDB-GENE-070912-173; -. DR CTD; 100170816; -. DR ZFIN; ZDB-GENE-070912-173; kirrel1b. DR Proteomes; UP000000437; Chromosome 2. DR GO; GO:0005911; C:cell-cell junction; IBA:GO_Central. DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central. DR GO; GO:0050839; F:cell adhesion molecule binding; IBA:GO_Central. DR GO; GO:0098609; P:cell-cell adhesion; IBA:GO_Central. DR GO; GO:0032836; P:glomerular basement membrane development; IMP:ZFIN. DR GO; GO:0072015; P:podocyte development; IMP:ZFIN. DR GO; GO:0039022; P:pronephric duct development; IMP:ZFIN. DR CDD; cd05898; IgI_5_KIRREL3; 1. DR Gene3D; 2.60.40.10; Immunoglobulins; 5. DR InterPro; IPR013162; CD80_C2-set. DR InterPro; IPR051275; Cell_adhesion_signaling. DR InterPro; IPR007110; Ig-like_dom. DR InterPro; IPR036179; Ig-like_dom_sf. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR013098; Ig_I-set. DR InterPro; IPR003599; Ig_sub. DR InterPro; IPR003598; Ig_sub2. DR PANTHER; PTHR11640:SF14; KIN OF IRRE-LIKE PROTEIN 1; 1. DR PANTHER; PTHR11640; NEPHRIN; 1. DR Pfam; PF08205; C2-set_2; 1. DR Pfam; PF07679; I-set; 1. DR Pfam; PF13927; Ig_3; 2. DR SMART; SM00409; IG; 5. DR SMART; SM00408; IGc2; 3. DR SUPFAM; SSF48726; Immunoglobulin; 5. DR PROSITE; PS50835; IG_LIKE; 5. PE 4: Predicted; KW Membrane {ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000000437}; KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT SIGNAL 1..23 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 24..783 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5035432570" FT TRANSMEM 512..536 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 25..119 FT /note="Ig-like" FT /evidence="ECO:0000259|PROSITE:PS50835" FT DOMAIN 124..220 FT /note="Ig-like" FT /evidence="ECO:0000259|PROSITE:PS50835" FT DOMAIN 227..303 FT /note="Ig-like" FT /evidence="ECO:0000259|PROSITE:PS50835" FT DOMAIN 312..392 FT /note="Ig-like" FT /evidence="ECO:0000259|PROSITE:PS50835" FT DOMAIN 396..498 FT /note="Ig-like" FT /evidence="ECO:0000259|PROSITE:PS50835" FT REGION 741..783 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 742..783 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 783 AA; 85827 MW; 60AA7DB56EB3C01D CRC64; MGFSMTCLWI VTLAIISVHR VFSGPRFSQE PADQSVVIGE RVVLSCVVFN YTGIVQWTKD GLALGIGEDL RAWPRYRVLR IMDVGQYNLE ITSADLTDDS LYECQATEAA LRSRRAKLTV LIPPDGPVIE GSPEILLTAG TSFNLTCVSR GAKPMSTIEW YKDGIIVEGA HTSTEVLSDR KRVTTKSFLE IQPMDTDTGR NFTCVASNLA APLGKRSTVT LNIHHPPTVI LSIEPRSVLE GERVKFTCQA TANPPIMGYR WAKGGVILDG ARESVFETTA DHSFFTEPVS CLVFNAVGST NVSILVDVHF GPILVVEPRP VTVDVDSDVT LNCKWSGNPP LTLTWTKKGS SMVLSNSNQL FLKSVSQADA GQYVCKAIVP RIGVGETEVT LTVNGPPIIS SEPIQYAVRG EKGEIKCYIA STPPPDKIVW AWKENVWEKE RGTLLERYTV EQSRPATQGG AVLSTLTINN VMEADFQSTY NCTAWNAFGP GTMIITLEET DIASEDIVPV GVIAGGSVGS SILLLLLLFA LIFYLYRQRK SSRRGVTLKP DIKVETVNKE TNLEEEAASA STATRMPFKD DMDLKQDLQT ETLEPKVEEY EAKDPTNGYY NVRATTHDEV RSSTRSLLYQ EFRAPNPASV SASTGGPANI HPAPTGRYEA RPTSRMAHNT YAHFNTIARA SQIQPPANPV SKTTDYPAER GLLESTNPLA FDSYAYSTTP QYRLGFAPPL EAGPAYEMYP TGQGVGTSQD ANVGKYPSSA QFPYSTPPTE YSQRHTQRMQ THV //