ID A0A8L7TBK0_BRUMA Unreviewed; 472 AA. AC A0A8L7TBK0; DT 03-AUG-2022, integrated into UniProtKB/TrEMBL. DT 03-AUG-2022, sequence version 1. DT 03-MAY-2023, entry version 5. DE SubName: Full=Type I phosphodiesterase / nucleotide pyrophosphatase family protein {ECO:0000313|WBParaSite:Bm5521.1}; GN Name=Bm1_06255 {ECO:0000313|WBParaSite:Bm5521.1}; OS Brugia malayi (Filarial nematode worm). OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia. OX NCBI_TaxID=6279 {ECO:0000313|Proteomes:UP000006672, ECO:0000313|WBParaSite:Bm5521.1}; RN [1] {ECO:0000313|Proteomes:UP000006672} RP NUCLEOTIDE SEQUENCE. RC STRAIN=FR3 {ECO:0000313|Proteomes:UP000006672}; RX PubMed=17885136; DOI=10.1126/science.1145406; RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E., RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T., RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L., RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M., RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J., RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F., RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W., RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M., RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J., RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E., RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G., RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B., RA Blaxter M.L., Scott A.L.; RT "Draft genome of the filarial nematode parasite Brugia malayi."; RL Science 317:1756-1760(2007). RN [2] {ECO:0000313|WBParaSite:Bm5521.1} RP IDENTIFICATION. RG WormBaseParasite; RL Submitted (APR-2022) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; XP_001892720.1; XM_001892685.1. DR GeneID; 6096178; -. DR KEGG; bmy:BM_BM5521; -. DR WBParaSite; Bm5521.1; Bm5521.1; WBGene00225782. DR CTD; 6096178; -. DR Proteomes; UP000006672; Unassembled WGS sequence. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW. DR CDD; cd16018; Enpp; 1. DR Gene3D; 3.30.1360.180; -; 1. DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1. DR InterPro; IPR017850; Alkaline_phosphatase_core_sf. DR InterPro; IPR002591; Phosphodiest/P_Trfase. DR PANTHER; PTHR10151; ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE; 1. DR PANTHER; PTHR10151:SF111; PROTEIN CBG02074; 1. DR Pfam; PF01663; Phosphodiest; 1. DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1. PE 4: Predicted; KW Membrane {ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000006672}; KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT SIGNAL 1..17 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 18..472 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5035475406" FT TRANSMEM 445..468 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" SQ SEQUENCE 472 AA; 54980 MW; 3A5957A4C8CA4680 CRC64; MWYCQYIFCI IAHFVAATEK IPCGQNLIVF IIDGYGKALL NQSDIGFRLL TQNGVYSDFL KPVYPTHNYP NWMSLVTGLY AENHGFGANY MWDRVKNRRF WKGETNRVGD SWWPDGVVPA WYTTGKSNVD VHCYWMPGCD LPYQDIIVQV PQERKYNASL PEQTDALMSY FPEIIERITK YQPYRQQFFL IRYAGVQAAL ETFGLRSDEL KQALINVDLS LLLLQQKLDA EKLFESTNLM VISTHGLYTV EQEEQFFIEE CLTDYSKIQK VVNHHAMMMI FTNPDEANEV FFELKLCDQW APMGDYDENE QPLVSVYQTT ELPDRFHWKN FQYMPEIVLI TRPGATVLTR ELPSLPPHDE QERDILLTGG WDNENLNMHG IFFARGPAFK EDYEASDINV VDIYQVMMNI FGIEPPHRHN GTWSNVEDFL SSGWETRSVP ENMRAFTVTS CQISLMCFTI LISSFMIYDQ FL //