ID A0A8I5KQG8_HUMAN Unreviewed; 108 AA. AC A0A8I5KQG8; DT 25-MAY-2022, integrated into UniProtKB/TrEMBL. DT 25-MAY-2022, sequence version 1. DT 29-MAY-2024, entry version 12. DE SubName: Full=Myelin transcription factor 1 like {ECO:0000313|Ensembl:ENSP00000509916.1}; GN Name=MYT1L {ECO:0000313|Ensembl:ENSP00000509916.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000509916.1, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000509916.1, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=15815621; DOI=10.1038/nature03466; RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., RA Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., RA Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., RA Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., RA Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., RA Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., RA Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., RA Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., RA Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., RA Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., RA Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., RA Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., RA Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., RA Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., RA Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., RA Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., RA Wilson R.K.; RT "Generation and annotation of the DNA sequences of human chromosomes 2 and RT 4."; RL Nature 434:724-731(2005). RN [2] {ECO:0000313|Ensembl:ENSP00000509916.1} RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2024) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC -!- SIMILARITY: Belongs to the MYT1 family. CC {ECO:0000256|ARBA:ARBA00010194}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC008276; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC009232; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC009471; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC011301; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC093390; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC106046; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR PeptideAtlas; A0A8I5KQG8; -. DR Ensembl; ENST00000689939.1; ENSP00000509916.1; ENSG00000186487.21. DR HGNC; HGNC:7623; MYT1L. DR GeneTree; ENSGT00940000155671; -. DR Proteomes; UP000005640; Chromosome 2. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter. DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR Gene3D; 4.10.320.30; -; 2. DR InterPro; IPR002515; Znf_C2H2C. DR InterPro; IPR036060; Znf_C2H2C_sf. DR PANTHER; PTHR10816:SF11; MYELIN TRANSCRIPTION FACTOR 1-LIKE PROTEIN; 1. DR PANTHER; PTHR10816; MYELIN TRANSCRIPTION FACTOR 1-RELATED; 1. DR Pfam; PF01530; zf-C2HC; 2. DR SUPFAM; SSF103637; CCHHC domain; 2. DR PROSITE; PS51802; ZF_CCHHC; 2. PE 1: Evidence at protein level; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242}; KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A8I5KQG8}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}; KW Repeat {ECO:0000256|ARBA:ARBA00022737}; KW Transcription {ECO:0000256|ARBA:ARBA00023163}; KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}; KW Zinc {ECO:0000256|ARBA:ARBA00022833}; KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE- KW ProRule:PRU01143}. SQ SEQUENCE 108 AA; 11590 MW; ACD00A43D2C9CB39 CRC64; MCFLFSLSGC PRAKKSGIRI AQSKEDKEDQ EPIRCPVPGC DGQGHITGKY ASHRSASGCP LAAKRQKDGY LNGSQFSWKS VKTEGMSCPT PGCDGSGHVS GSFLTHRR //