ID A0A8H4C1F0_YEASX Unreviewed; 1471 AA. AC A0A8H4C1F0; DT 19-JAN-2022, integrated into UniProtKB/TrEMBL. DT 19-JAN-2022, sequence version 1. DT 22-FEB-2023, entry version 6. DE SubName: Full=MYO4 isoform 1 {ECO:0000313|EMBL:KAF1906050.1}; GN Name=MYO4 {ECO:0000313|EMBL:KAF1906050.1}; GN ORFNames=GI527_G0000037 {ECO:0000313|EMBL:KAF1906050.1}; OS Saccharomyces cerevisiae (Baker's yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=4932 {ECO:0000313|EMBL:KAF1906050.1, ECO:0000313|Proteomes:UP000470054}; RN [1] {ECO:0000313|EMBL:KAF1906050.1, ECO:0000313|Proteomes:UP000470054} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=INSC1005 {ECO:0000313|EMBL:KAF1906050.1, RC ECO:0000313|Proteomes:UP000470054}; RA Fiddes I.T., Church D.M.; RT "Inscripta technologies."; RL Submitted (JAN-2020) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:KAF1906050.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JAAEAL010000008; KAF1906050.1; -; Genomic_DNA. DR SMR; A0A8H4C1F0; -. DR Proteomes; UP000470054; Chromosome i. DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW. DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule. DR GO; GO:0051641; P:cellular localization; IEA:UniProt. DR GO; GO:0006996; P:organelle organization; IEA:UniProt. DR CDD; cd15479; fMyo4p_CBD; 1. DR CDD; cd01380; MYSc_Myo5; 1. DR Gene3D; 1.10.10.820; -; 1. DR Gene3D; 1.20.5.190; -; 1. DR Gene3D; 1.20.5.4820; -; 1. DR Gene3D; 1.20.58.530; -; 1. DR Gene3D; 3.40.850.10; Kinesin motor domain; 1. DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1. DR InterPro; IPR002710; Dilute_dom. DR InterPro; IPR000048; IQ_motif_EF-hand-BS. DR InterPro; IPR036961; Kinesin_motor_dom_sf. DR InterPro; IPR001609; Myosin_head_motor_dom. DR InterPro; IPR004009; Myosin_N. DR InterPro; IPR036103; MYSc_Myo5. DR InterPro; IPR027417; P-loop_NTPase. DR PANTHER; PTHR13140:SF836; DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C; 1. DR PANTHER; PTHR13140; MYOSIN; 1. DR Pfam; PF01843; DIL; 1. DR Pfam; PF00612; IQ; 1. DR Pfam; PF00063; Myosin_head; 1. DR PRINTS; PR00193; MYOSINHEAVY. DR SMART; SM01132; DIL; 1. DR SMART; SM00015; IQ; 4. DR SMART; SM00242; MYSc; 1. DR SUPFAM; SSF50084; Myosin S1 fragment, N-terminal domain; 1. DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1. DR PROSITE; PS51126; DILUTE; 1. DR PROSITE; PS50096; IQ; 2. DR PROSITE; PS51456; MYOSIN_MOTOR; 1. DR PROSITE; PS51844; SH3_LIKE; 1. PE 3: Inferred from homology; KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782}; KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00782}; KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE- KW ProRule:PRU00782}; KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE- KW ProRule:PRU00782}; KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00782}. FT DOMAIN 4..57 FT /note="Myosin N-terminal SH3-like" FT /evidence="ECO:0000259|PROSITE:PS51844" FT DOMAIN 71..777 FT /note="Myosin motor" FT /evidence="ECO:0000259|PROSITE:PS51456" FT DOMAIN 1164..1419 FT /note="Dilute" FT /evidence="ECO:0000259|PROSITE:PS51126" FT REGION 647..669 FT /note="Actin-binding" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782" FT BINDING 165..172 FT /ligand="ATP" FT /ligand_id="ChEBI:CHEBI:30616" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:KAF1906050.1" SQ SEQUENCE 1471 AA; 169344 MW; E79C0FE72B041E95 CRC64; MSFEVGTKCW YPHKEQGWIG GEVTKNDFFE GTFHLELKLE DGETVSIETN SFENDDDHPT LPVLRNPPIL ESTDDLTTLS YLNEPAVLHA IKKRYMNGQI YTYSGIVLIA ANPFDKVDHL YSREMIQNYS SKRKDELEPH LFAIAEEAYR FMVHEKANQT VVVSGESGAG KTVSAKYIMR YFASVQESNN REGEVEMSQI ESQILATNPI MEAFGNAKTT RNDNSSRFGK YLQILFDENT TIRGSKIRTY LLEKSRLVYQ PETERNYHIF YQILEGLPEP VKQELHLSSP KDYHYTNQGG QPNIAGIDEA REYKITTDAL SLVGINHETQ LGIFKILAGL LHIGNIEMKM TRNDASLSSE EQNLQIACEL LGIDPFNFAK WIVKKQIVTR SEKIVTNLNY NQALIARDSV AKFIYSTLFD WLVDNINKTL YDPELDQQDH VFSFIGILDI YGFEHFEKNS FEQFCINYAN EKLQQEFNQH VFKLEQEEYV KEEIEWSFIE FSDNQPCIDL IENKLGILSL LDEESRLPSG SDESWASKLY SAFNKPPSNE VFSKPRFGQT KFIVSHYAVD VEYEVEGFIE KNRDSVSLGH LDVFKATTNP IFKQILDNRE LRSDDAPEEQ NTEKKIMIPA RLSQKKPTLG SMFKKSLGEL MAIINSTNVH YIRCIKPNSE KKPWEFDNLM VLSQLRACGV LETIRISCAG FPSRWTFDEF VQRYFLLTDY SLWSGILYNP DLPKEAIVNF CQSILDATIS DSAKYQIGNT KIFFKAGMLA FLEKLRTNKM NEICIIIQKK IRARYYRLQY LQTMESIKKC QSQIRSLLVR TRVDHELKTR AAILLQTNIR ALWKREYYRA AIGQIIKLQC TCKRKLILDS VNRKFMLMAA VIIQSYIRSY GHKTDYRTLK RSSILVQSAM RMQLARRRYI VLQKEVEERN IRASYGIGLL EEAIEFKNSF ILNLEMLNDS YTRLTQLLQG DLSNIPSKQR QEYETIVNGY NDKISKLKTL QVEIMNTLNK KNALKERKKK QSSLIQSHMQ SLAAIKGNKP SRLSDEVKSM KQELAFIENV IAQDFTTTYS ANKNDKVKGL GIAGQQVKPK LVNVIRRESG NPDLLELLMD LNCYTLEVTE GYLKKVNVTE VNGDNVLGPI HVITTVVSSL VRNGLLIQSS KFISKVLLTV ESIVMSLPKD ETMLGGIFWL SNLSRLPAFA ANQKTLYEAN GGDEKDKLTL IYLNDLENET LKVFDKIYST WLVKFMKHAS AHIEIFDMVL NEKLFKNSGD EKFAKLFTFL NEFDAVLCKF QVVDSMHTKI FNDTLKYLNV MLFNDLITKC PALNWKYGYE VDRNIERLVS WFEPRIEDVR PNLIQIIQAV KILQLKISNL NEFKLLFDFW YALNPAQIQA ILLKYKPANK GEAGVPNEIL NYLANVIKRE NLSLPGKMEI MLSAQFDSAK NHLRYDTSAI TQNSNTEGLA TVSKIIKLDR K //