ID A0A8F6T6B3_9LAMI Unreviewed; 771 AA. AC A0A8F6T6B3; DT 19-JAN-2022, integrated into UniProtKB/TrEMBL. DT 19-JAN-2022, sequence version 1. DT 29-MAY-2024, entry version 8. DE SubName: Full=Nezukol synthase {ECO:0000313|EMBL:QXT24228.1}; DE EC=4.2.3.183 {ECO:0000313|EMBL:QXT24228.1}; GN Name=KSL5 {ECO:0000313|EMBL:QXT24228.1}; OS Isodon lophanthoides var. gerardianus. OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Ocimeae; Isodoninae; OC Isodon. OX NCBI_TaxID=669302 {ECO:0000313|EMBL:QXT24228.1}; RN [1] {ECO:0000313|EMBL:QXT24228.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=34133748; RA Yang R., Du Z., Qiu T., Sun J., Shen Y., Huang L.; RT "Discovery and Functional Characterization of a Diverse Diterpene Synthase RT Family in the Medicinal Herb Isodon lophanthoides var. Gerardiana."; RL Plant Cell Physiol. 0:0-0(2021). CC -!- COFACTOR: CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420; CC Evidence={ECO:0000256|ARBA:ARBA00001946}; CC -!- PATHWAY: Secondary metabolite biosynthesis; terpenoid biosynthesis. CC {ECO:0000256|ARBA:ARBA00004721}. CC -!- SIMILARITY: Belongs to the terpene synthase family. CC {ECO:0000256|ARBA:ARBA00006333}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; MW251829; QXT24228.1; -; mRNA. DR GO; GO:0009507; C:chloroplast; IEA:TreeGrafter. DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro. DR GO; GO:0010333; F:terpene synthase activity; IEA:InterPro. DR GO; GO:0009686; P:gibberellin biosynthetic process; IEA:TreeGrafter. DR GO; GO:0042214; P:terpene metabolic process; IEA:UniProt. DR Gene3D; 1.50.10.160; -; 1. DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1. DR Gene3D; 1.50.10.130; Terpene synthase, N-terminal domain; 1. DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf. DR InterPro; IPR001906; Terpene_synth_N. DR InterPro; IPR036965; Terpene_synth_N_sf. DR InterPro; IPR005630; Terpene_synthase_metal-bd. DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase. DR PANTHER; PTHR31739:SF33; BETA-PHELLANDRENE SYNTHASE (NERYL-DIPHOSPHATE-CYCLIZING), CHLOROPLASTIC; 1. DR PANTHER; PTHR31739; ENT-COPALYL DIPHOSPHATE SYNTHASE, CHLOROPLASTIC; 1. DR Pfam; PF01397; Terpene_synth; 1. DR Pfam; PF03936; Terpene_synth_C; 1. DR SFLD; SFLDG01014; Terpene_Cyclase_Like_1_N-term; 1. DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2. DR SUPFAM; SSF48576; Terpenoid synthases; 1. PE 2: Evidence at transcript level; KW Lyase {ECO:0000313|EMBL:QXT24228.1}; KW Magnesium {ECO:0000256|ARBA:ARBA00022842}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}. FT DOMAIN 214..399 FT /note="Terpene synthase N-terminal" FT /evidence="ECO:0000259|Pfam:PF01397" FT DOMAIN 479..703 FT /note="Terpene synthase metal-binding" FT /evidence="ECO:0000259|Pfam:PF03936" SQ SEQUENCE 771 AA; 88076 MW; 9DBC84186EA99453 CRC64; MSALKLIPFS TSIDKQFSGR TSILGCKCSL QIDVPKTKAQ KILGEKIRKR ISNGKVEMSP SAYDTAWVAM VPSREFSGRP NFPECLDWIV ENQNPDGSWG LNLGHPFLVK DSLSCTLACL LALRKWDVAN HILHKGIEFM KANWRAATDD ENQVSPIGFN IIFPGMIEFA KELDLTLPLP PSSLNALLRA RDSEIMRQRN WEYVAEGLGE SCNWNQIILK HQTRNGSLFN SPATTAAAAI HCRDDNCFDY LISVVNKCNG WAPTVFPMDI YARLCMIDTL QRLGIDRHFR VELDTVFDEM YRKWEEREEE MFSDVSCQAL AFRLLRVKGY DVSSDGLEEF VEQEGFLDSV GMQHSSVGTV VELYRASQTR INEEENILHK INAWTKPFLT RQTIHKKKQV EYELKNYYGT VDRFLHRRTI DLHHAQPSQI LKTSYCCSAI HNQDFIRFAV ENFKICREEY LKELDEINKW YAYFGMDLLS KGRNACEQSY VVTAGLIADV ELSMARISFA QVAILITVFD DVFDRYGTRE EALAIIQLIK EWEPAPSDCS ELVKTTYTAL YDTVNETTAK AHAQQGFCFK QQIISMWVEL LESAVREKES LSGKNVSTLD EYLSFAPITI GCKLCVLTSV HFLGIQLSEE MLTSAEMLTL CWHGNVVCRL LNDLKTYSRE REENTVNSVS VQTGVSEEEA VSKVKEVLEY HRRKVMKMVY QSKGSNVPRE CKEMVWKTCK VAHCFYGYDG DEFSSPRDII EDINAMMFHD LPRLSADACS T //