ID   A0A8F3FJE1_9ASTR        Unreviewed;       363 AA.
AC   A0A8F3FJE1;
DT   19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2022, sequence version 1.
DT   03-AUG-2022, entry version 3.
DE   RecName: Full=NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic {ECO:0000256|HAMAP-Rule:MF_01350};
DE            EC=7.1.1.- {ECO:0000256|HAMAP-Rule:MF_01350};
DE   AltName: Full=NAD(P)H dehydrogenase subunit 1 {ECO:0000256|HAMAP-Rule:MF_01350};
DE            Short=NDH subunit 1 {ECO:0000256|HAMAP-Rule:MF_01350};
DE   AltName: Full=NADH-plastoquinone oxidoreductase subunit 1 {ECO:0000256|HAMAP-Rule:MF_01350};
GN   Name=ndhA {ECO:0000256|HAMAP-Rule:MF_01350,
GN   ECO:0000313|EMBL:QWZ47225.1};
OS   Cyclocodon parviflorus.
OG   Plastid; Chloroplast {ECO:0000313|EMBL:QWZ47225.1}.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Asterales; Campanulaceae; Cyclocodon.
OX   NCBI_TaxID=2851912 {ECO:0000313|EMBL:QWZ47225.1};
RN   [1] {ECO:0000313|EMBL:QWZ47225.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=32407424;
RA   Li C.J., Wang R.N., Li D.Z.;
RT   "Comparative analysis of plastid genomes within the Campanulaceae and
RT   phylogenetic implications.";
RL   PLoS ONE 15:0-e0233167(2020).
RN   [2] {ECO:0000313|EMBL:QWZ47225.1}
RP   NUCLEOTIDE SEQUENCE.
RG   Cyclocodon parviflorus;
RA   WangLi C.;
RL   Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN
CC       and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain
CC       and possibly in a chloroplast respiratory chain. The immediate electron
CC       acceptor for the enzyme in this species is believed to be
CC       plastoquinone. Couples the redox reaction to proton translocation, and
CC       thus conserves the redox energy in a proton gradient.
CC       {ECO:0000256|HAMAP-Rule:MF_01350}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n
CC         H(+)(out) + NAD(+); Xref=Rhea:RHEA:42608, Rhea:RHEA-COMP:9561,
CC         Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757,
CC         ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:62192;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_01350,
CC         ECO:0000256|RuleBase:RU000474};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n
CC         H(+)(out) + NADP(+); Xref=Rhea:RHEA:42612, Rhea:RHEA-COMP:9561,
CC         Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757,
CC         ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:62192;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_01350,
CC         ECO:0000256|RuleBase:RU000474};
CC   -!- SUBUNIT: NDH is composed of at least 16 different subunits, 5 of which
CC       are encoded in the nucleus. {ECO:0000256|HAMAP-Rule:MF_01350,
CC       ECO:0000256|RuleBase:RU000474}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU000471};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU000471}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}. Plastid, chloroplast thylakoid
CC       membrane {ECO:0000256|HAMAP-Rule:MF_01350,
CC       ECO:0000256|RuleBase:RU000474}; Multi-pass membrane protein
CC       {ECO:0000256|HAMAP-Rule:MF_01350, ECO:0000256|RuleBase:RU000474}.
CC   -!- SIMILARITY: Belongs to the complex I subunit 1 family.
CC       {ECO:0000256|ARBA:ARBA00010535, ECO:0000256|HAMAP-Rule:MF_01350,
CC       ECO:0000256|RuleBase:RU000471}.
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DR   EMBL; MT074353; QWZ47225.1; -; Genomic_DNA.
DR   EMBL; MT074353; QWZ47236.1; -; Genomic_DNA.
DR   GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; IEA:UniProtKB-UniRule.
DR   GO; GO:0048038; F:quinone binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0019684; P:photosynthesis, light reaction; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01350; NDH1_NuoH; 1.
DR   InterPro; IPR001694; NADH_UbQ_OxRdtase_su1/FPO.
DR   InterPro; IPR018086; NADH_UbQ_OxRdtase_su1_CS.
DR   PANTHER; PTHR11432; PTHR11432; 1.
DR   Pfam; PF00146; NADHdh; 1.
DR   PROSITE; PS00667; COMPLEX1_ND1_1; 1.
DR   PROSITE; PS00668; COMPLEX1_ND1_2; 1.
PE   3: Inferred from homology;
KW   Chloroplast {ECO:0000256|RuleBase:RU000474, ECO:0000313|EMBL:QWZ47225.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01350};
KW   NAD {ECO:0000256|HAMAP-Rule:MF_01350, ECO:0000256|RuleBase:RU000471};
KW   NADP {ECO:0000256|HAMAP-Rule:MF_01350, ECO:0000256|RuleBase:RU000474};
KW   Plastid {ECO:0000256|RuleBase:RU000474, ECO:0000313|EMBL:QWZ47225.1};
KW   Plastoquinone {ECO:0000256|HAMAP-Rule:MF_01350,
KW   ECO:0000256|RuleBase:RU000474};
KW   Quinone {ECO:0000256|HAMAP-Rule:MF_01350, ECO:0000256|RuleBase:RU000474};
KW   Thylakoid {ECO:0000256|HAMAP-Rule:MF_01350, ECO:0000256|RuleBase:RU000474};
KW   Translocase {ECO:0000256|HAMAP-Rule:MF_01350,
KW   ECO:0000256|RuleBase:RU000474};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW   Rule:MF_01350};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW   Rule:MF_01350}.
FT   TRANSMEM        26..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01350,
FT                   ECO:0000256|RuleBase:RU000474"
FT   TRANSMEM        97..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01350,
FT                   ECO:0000256|RuleBase:RU000474"
FT   TRANSMEM        122..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01350,
FT                   ECO:0000256|RuleBase:RU000474"
FT   TRANSMEM        255..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01350,
FT                   ECO:0000256|RuleBase:RU000474"
FT   TRANSMEM        297..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01350,
FT                   ECO:0000256|RuleBase:RU000474"
FT   TRANSMEM        343..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01350,
FT                   ECO:0000256|RuleBase:RU000474"
SQ   SEQUENCE   363 AA;  40224 MW;  100DAC6C80732C39 CRC64;
     MIIDTTEVQA INSFSRLESL KEIYEIIWML VPIFTPVLGI TIGVLVIVWL EREISAGIQQ
     RIGPEYAGPL GILQALADGT KLLFKENLLP SRGDTRLFSI GPPIAVISIL LSYLVIPFGY
     HLVLADLSIG VFLWIAISSI APVGLLMSGY GSNNKYSFLG GLRAAAQSIS YEIPLTLCVL
     SISLLSNSSS TIDIVEAQSK HGFWGWNLWR QPIGFLVFLI SSLAECERLP FDLPEAEEEL
     VAGYQTEYSG IKFGLFYVVS YLNLLVSSLF VTVLYLGGWN LSILHISVPG LFEIKKAGRV
     FVTLIGIFIT LAKTYLFLFI PITTRWTLPR LRMDQLLNLG WKFLLPISLG NLLLTTSSQL
     LSL
//