ID A0A8D2EU63_THEGE Unreviewed; 871 AA. AC A0A8D2EU63; DT 19-JAN-2022, integrated into UniProtKB/TrEMBL. DT 19-JAN-2022, sequence version 1. DT 08-NOV-2023, entry version 10. DE RecName: Full=Coiled-coil alpha-helical rod protein 1 {ECO:0000256|ARBA:ARBA00016468}; DE AltName: Full=Alpha-helical coiled-coil rod protein {ECO:0000256|ARBA:ARBA00031932}; GN Name=LOC112623369 {ECO:0000313|Ensembl:ENSTGEP00000010423.1}; OS Theropithecus gelada (Gelada baboon). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; OC Cercopithecidae; Cercopithecinae; Theropithecus. OX NCBI_TaxID=9565 {ECO:0000313|Ensembl:ENSTGEP00000010423.1, ECO:0000313|Proteomes:UP000694411}; RN [1] {ECO:0000313|Ensembl:ENSTGEP00000010423.1} RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2023) to UniProtKB. CC -!- FUNCTION: May be a regulator of keratinocyte proliferation or CC differentiation. {ECO:0000256|ARBA:ARBA00003936}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. CC Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR Ensembl; ENSTGET00000012545.1; ENSTGEP00000010423.1; ENSTGEG00000008533.1. DR Proteomes; UP000694411; Chromosome 4. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0030154; P:cell differentiation; IEA:InterPro. DR InterPro; IPR009800; HCR. DR PANTHER; PTHR46822; COILED-COIL ALPHA-HELICAL ROD PROTEIN 1; 1. DR PANTHER; PTHR46822:SF1; COILED-COIL ALPHA-HELICAL ROD PROTEIN 1; 1. DR Pfam; PF07111; HCR; 1. PE 4: Predicted; KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils}; KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242}; KW Reference proteome {ECO:0000313|Proteomes:UP000694411}. FT REGION 268..307 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COILED 173..221 FT /evidence="ECO:0000256|SAM:Coils" FT COILED 448..552 FT /evidence="ECO:0000256|SAM:Coils" FT COILED 587..763 FT /evidence="ECO:0000256|SAM:Coils" FT COMPBIAS 268..298 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 871 AA; 99319 MW; F45FB079EBCCC9F6 CRC64; MWPHSAGARP WASTLIGKDP RVMAWWCLDG IPPGLAEPWR ELWRWRSRPL HCVPPFSPLA RGSRDHRNLK RRGNIDGWRQ NLEPSNNVEM FPPSDSTGLI PPSHFQARPL STLPRMAPTW LSDIPLVQPP GHQDVSERRL DTQRPQVTMW KQDVSSDRQE PGRRGRSWEL EGSQALSQQA EVIARQLQEL RRLEEEVRLL RETSLQQKMR LEAQAMELEA LAQAEKAGRA EAEGLRAALA GAEVVRKNLE EGSQRELEEV QRLHQEQLSS LTQAHQEALS SLTSKAEGLE QSLSSLETRR AGEAKELAEA QREAELLRKQ LSKTQEDLEA QVTLVENLRK YVGEQVPPEV HSQTWELERQ KFLENMHHLQ EDRDGLHATA ELLQVRVQSL THILALQEEE LTRKVQPSDS LEPEFTRKCQ SLLNRWREKV FALMVQLKAQ ELEHSDSVKQ LKGQVTSLQE QVTAQSQEQA ILQRSLQDKA AEVEVERMGS RGLQLELSRA QEARRRWQQQ TTAAEEQLRL VVNAVSSSQI WLESTMAKVE EAAARLPSLN NRLSYAVRKV HTIRGLTARK LALAQLRQES CPLPPPVTDV SLELQQLREE RNRLDAELQL SARLIQQEVG RAREQGEAER QQLSKVAQQL EQELQQTQES LASLGLQLEV ARQGQQESTE EAASLRQELT QQQDLYRQAL QEKVAEVETR LREQLADTER RLNEARREHA KAVVSLRQIQ RRAAQEKERS QELRRLQEEA RKEEGQRLAW RLQELERDKN LMLATLQQEG LLSRYKQQRL LAVLPSLLDK KKSVVSSPRP PECSASVPVA AAVPTRESIK GSLSVLLDDL QGLSEAISKE EAVCQGDNLD RCSSSNPQMS S //