ID   A0A8D1SA69_PIG          Unreviewed;       266 AA.
AC   A0A8D1SA69;
DT   19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2022, sequence version 1.
DT   27-MAR-2024, entry version 9.
DE   RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE            EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN   Name=ECHDC2 {ECO:0000313|Ensembl:ENSSSCP00055048702.1};
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00055048702.1, ECO:0000313|Proteomes:UP000694724};
RN   [1] {ECO:0000313|Ensembl:ENSSSCP00055048702.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC         methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC         ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00001709};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   Ensembl; ENSSSCT00030021725.1; ENSSSCP00030009833.1; ENSSSCG00030015625.1.
DR   Ensembl; ENSSSCT00035076834.1; ENSSSCP00035031403.1; ENSSSCG00035057421.1.
DR   Ensembl; ENSSSCT00040082533.1; ENSSSCP00040035940.1; ENSSSCG00040059695.1.
DR   Ensembl; ENSSSCT00055060775.1; ENSSSCP00055048702.1; ENSSSCG00055030496.1.
DR   Ensembl; ENSSSCT00060092266.1; ENSSSCP00060039873.1; ENSSSCG00060067576.1.
DR   Proteomes; UP000694570; Unplaced.
DR   Proteomes; UP000694720; Unplaced.
DR   Proteomes; UP000694722; Unplaced.
DR   Proteomes; UP000694723; Unplaced.
DR   Proteomes; UP000694724; Unplaced.
DR   CDD; cd06558; crotonase-like; 1.
DR   Gene3D; 1.10.12.10; Lyase 2-enoyl-coa Hydratase, Chain A, domain 2; 1.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR045004; ECH_dom.
DR   InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR   InterPro; IPR014748; Enoyl-CoA_hydra_C.
DR   PANTHER; PTHR11941:SF44; ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 2, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11941; ENOYL-COA HYDRATASE-RELATED; 1.
DR   Pfam; PF00378; ECH_1; 1.
DR   Pfam; PF16113; ECH_2; 1.
DR   SUPFAM; SSF52096; ClpP/crotonase; 1.
PE   4: Predicted;
FT   DOMAIN          49..111
FT                   /note="Enoyl-CoA hydratase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF16113"
SQ   SEQUENCE   266 AA;  28896 MW;  3E997983050824AA CRC64;
     MLRTLASALR PPRRWRPLEK TRGCASSPVD AGREIQVRAL EGLDQGITEI LMNRPSARNA
     LGNVFVSQLL EALAQLREDR HVRVLIFRSG VKGVFCAGAD LKEREQMSEA EVGVFVQRLR
     GLMNEIASSA VMGLIETTRG LLPGAGGTQR LPRCLGVALA KELIFTGRRL SGMQAQALGL
     VNHAVAQNEE GNAAYHRALA LAQEILPQAP IAVRLGKLAI DRGIEVDIAS GMAIEGICYA
     QNIPTRDRLE GMAAFREKRT PKFVGE
//