ID A0A8D1FB21_PIG Unreviewed; 393 AA. AC A0A8D1FB21; DT 19-JAN-2022, integrated into UniProtKB/TrEMBL. DT 19-JAN-2022, sequence version 1. DT 03-MAY-2023, entry version 6. DE RecName: Full=PAS-4 {ECO:0000256|Google:ProtNLM}; OS Sus scrofa (Pig). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus. OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00040032753.1, ECO:0000313|Proteomes:UP000694722}; RN [1] {ECO:0000313|Ensembl:ENSSSCP00040032753.1} RP IDENTIFICATION. RG Ensembl; RL Submitted (JAN-2023) to UniProtKB. CC -!- SIMILARITY: Belongs to the CD36 family. CC {ECO:0000256|ARBA:ARBA00010532}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR Ensembl; ENSSSCT00035076818.1; ENSSSCP00035031394.1; ENSSSCG00035057183.1. DR Ensembl; ENSSSCT00040076228.1; ENSSSCP00040032753.1; ENSSSCG00040045688.1. DR Ensembl; ENSSSCT00045065334.1; ENSSSCP00045046230.1; ENSSSCG00045037617.1. DR Ensembl; ENSSSCT00060043742.1; ENSSSCP00060018662.1; ENSSSCG00060031988.1. DR Ensembl; ENSSSCT00065078150.1; ENSSSCP00065033989.1; ENSSSCG00065056849.1. DR Proteomes; UP000694720; Unplaced. DR Proteomes; UP000694722; Unplaced. DR Proteomes; UP000694723; Unplaced. DR Proteomes; UP000694725; Unplaced. DR Proteomes; UP000694728; Unplaced. DR GO; GO:0005886; C:plasma membrane; IEA:UniProt. DR InterPro; IPR005428; CD36/SCARB1/SNMP1. DR InterPro; IPR002159; CD36_fam. DR PANTHER; PTHR11923:SF12; PLATELET GLYCOPROTEIN 4; 1. DR PANTHER; PTHR11923; SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1; 1. DR Pfam; PF01130; CD36; 1. DR PRINTS; PR01610; CD36ANTIGEN. DR PRINTS; PR01609; CD36FAMILY. PE 3: Inferred from homology; KW Disulfide bond {ECO:0000256|PIRSR:PIRSR605428-52}; KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180}; KW Isopeptide bond {ECO:0000256|PIRSR:PIRSR605428-51}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}; KW Ubl conjugation {ECO:0000256|PIRSR:PIRSR605428-51}. FT TRANSMEM 61..83 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 359..384 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT SITE 384 FT /note="Critical for TLR4-TLR6 dimerization and signaling" FT /evidence="ECO:0000256|PIRSR:PIRSR605428-50" FT DISULFID 164..232 FT /evidence="ECO:0000256|PIRSR:PIRSR605428-52" FT DISULFID 193..254 FT /evidence="ECO:0000256|PIRSR:PIRSR605428-52" FT DISULFID 234..243 FT /evidence="ECO:0000256|PIRSR:PIRSR605428-52" FT CROSSLNK 390 FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with FT G-Cter in ubiquitin)" FT /evidence="ECO:0000256|PIRSR:PIRSR605428-51" SQ SEQUENCE 393 AA; 44308 MW; 1D24F188CB38403F CRC64; SGMEGNLSVK QKLYSIRYLA KKNIVQDPKT HTVSFLQPKG AIFEPSLSVG TENDTFTVLN LAVAAAPHLY PSAFIQLILN VFIKRSKSSM FQKRTLKELL WGYTDPFLNL IPYSTPTTVG MFYPHHNTSD GVYKVFSGKN DASKVAIIDS YKGKKNLPYW PSYCGMINGT DGASFPPFIE KTRVLRFFAS EICRSFYAVF GAEVNLKGIP VYRFILPSMT FASPLQNPEN RCFCTEKIIS KNCTLYGVLD ISKCKEGKPV YISLPHFLHA SPEIAKTIEG LNPNQEEHST YLDVEPITGF TLRFAQRLQI NLLVKPARII EALKNLKQNY IVPVLWLNET GTISDEKAEM FRKQVTEKIN LLGLVEMILL SVGVVMFIAF MISYCTCRSK KVN //